In an orthotopic brain tumor mouse model, it was shown that convection-enhanced intratumoral delivery of a theranostic metallofullerene (f-Gd3N@C80) labeled with lutetium 177(177Lu) and tetraazacyclododecane tetraacetic acid (DOTA)(177Lu-DOTA-f- Gd3N@C80) increases median survival from 21 to 52 days, with a prolonged metallofullerene tumor retention that can be visualized with magnetic resonance (MR) imaging.
|Original language||English (US)|
|Number of pages||2|
|State||Published - Oct 1 2011|
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging