TY - JOUR
T1 - Schizophrenia as a developmental disorder of the cerebral cortex
AU - Raedler, Thomas J.
AU - Knable, Michael B.
AU - Weinberger, Daniel R.
PY - 1998/2
Y1 - 1998/2
N2 - The hypothesis that schizophrenia results from a developmental, as opposed to a degenerative, process affecting the cerebral cortex has become popular in current thinking about the disorder. While many of the data gathered in support of this hypothesis do not in themselves represent conclusive proof, an intriguing picture is emerging from a variety of research approaches. These approaches include the observation of minor physical anomalies, premorbid neuropsychological and social deficits, obstetrical complications, and exposure to adverse intrauterine events. Morphometric brain measurement techniques and neuropathological studies have perhaps provided more substantial support.
AB - The hypothesis that schizophrenia results from a developmental, as opposed to a degenerative, process affecting the cerebral cortex has become popular in current thinking about the disorder. While many of the data gathered in support of this hypothesis do not in themselves represent conclusive proof, an intriguing picture is emerging from a variety of research approaches. These approaches include the observation of minor physical anomalies, premorbid neuropsychological and social deficits, obstetrical complications, and exposure to adverse intrauterine events. Morphometric brain measurement techniques and neuropathological studies have perhaps provided more substantial support.
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U2 - 10.1016/S0959-4388(98)80019-6
DO - 10.1016/S0959-4388(98)80019-6
M3 - Article
C2 - 9568403
AN - SCOPUS:0031943325
SN - 0959-4388
VL - 8
SP - 157
EP - 161
JO - Current Opinion in Neurobiology
JF - Current Opinion in Neurobiology
IS - 1
ER -