Schizophrenia and Infections: The Eyes Have It

E. Fuller Torrey, Robert H. Yolken

Research output: Contribution to journalReview article

Abstract

The visual tract is prominently involved in schizophrenia, as evidenced by perceptual distortions and a type of nystagmus found in many individuals affected. Genetic explanations for these abnormalities have been suggested. This study proposes an alternate explanation based on infection. Several infectious agents thought to be associated with some cases of schizophrenia are known to cause both infection of the fetus and abnormalities of the eye. Toxoplasma gondii is examined in detail, and rubella, cytomegalovirus, varicella-zoster virus, and herpes simplex virus more briefly. Careful ophthalmic assessments, including funduscopy and direct examination of tissues for infectious agents, will clarify the role of such agents in ocular aspects of schizophrenia.

Original languageEnglish (US)
Pages (from-to)247-252
Number of pages6
JournalSchizophrenia bulletin
Volume43
Issue number2
DOIs
StatePublished - Mar 1 2017

Keywords

  • infections
  • ocular
  • schizophrenia
  • toxoplasmosis

ASJC Scopus subject areas

  • Psychiatry and Mental health

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