Schizophrenia

Sofya Abazyan, Mikhail V. Pletnikov

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Schizophrenia is a major psychiatric disorder afecting approximately 1% of the population. It has been identiied as one of the tenmost debilitating diseases (WorldHealthOrganization). Schizophrenia is characterized by positive, negative, disorganization, cognitive, psychomotor, and mood symptoms (Tandon et al., 2009). The severity of diferent symptoms varies between patients and through the course of the illness. Although the onset of the disease is in late adolescence or early adulthood, subtle motor, cognitive, and social abnormalities are present prior to the onset of the disease, with cognitive impairments persisting throughout the entire course of the illness (Insel, 2010).

Original languageEnglish (US)
Title of host publicationBehavioral Genetics of the Mouse Volume II
Subtitle of host publicationGenetic Mouse Models of Neurobehavioral Disorders
PublisherCambridge University Press
Pages189-207
Number of pages19
ISBN (Electronic)9781107360556
ISBN (Print)9781107044456
DOIs
StatePublished - Jan 1 2014

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)

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    Abazyan, S., & Pletnikov, M. V. (2014). Schizophrenia. In Behavioral Genetics of the Mouse Volume II: Genetic Mouse Models of Neurobehavioral Disorders (pp. 189-207). Cambridge University Press. https://doi.org/10.1007/CBO9781107360556