Magyar szkizofrénia-biobank a szkizofréniakutatás és a személyre szabott orvoslás szolgálatában

Translated title of the contribution: SCHIZOBANK - The Hungarian national schizophrenia biobank and its role in schizophrenia research

Gabriella Inczédy-Farkas, Judit Benkovits, Nóra Balogh, Péter Álmos, Beáta Scholtz, Gábor Zahuczky, Zsolt Török, Krisztián Nagy, János Réthelyi, Zoltán Makkos, Ákos Kassai-Farkas, Anikó Igerházy, Judit Tuzko, Zoltán Janka, István Bitter, György Németh, László Nagy, Mária Judit Molnár

Research output: Contribution to journalArticlepeer-review

Abstract

Delineating the pathogenesis of multifactorial diseases is a major challenge of the postgenomial era. Genetic factors are known to play an important role in the pathogenesis of certain psychiatric disorders as well as in the development of adverse reactions to psychoactive drugs. Containing large numbers of samples and linking them clinical data, biobanks are gaining importance in the studies of chronic multifactorial diseases. Several biobanks are under establishment in Hungary. The first initiative to collect samples in neurological and psychiatric disorders was the NEPSYBANK coordinated by the Hungarian Society of Clinical Neurogenetics. The national biobank network is currently established by the NEKIFUT project of the National Office of Research and Technology. In this article we describe the structure, logistics and informatical background of the national schizophrenia biobank (SCHIZOBANK). The initiative of the SCHIZOBANK originates from a consortium in which academy and health industry partners are collecting biological materials and data in five major psychiatric center under the coordination of the Medical and Health Science Center of the University of Debrecen. We review other international schizophrenia biobanks as well. Major strength of the SCHIZOBANK is the collection of very detailed phenotypic data and of RNA and plasma both in psychotic and non-psychotic state of the patient which permits longitudinal follow-up and the study of both static and dynamically changing transcriptomic, proteomic and metabolomic markers. The collection of the SCHIZOBANK is available not only to consortial partners but to other national and international research groups as well.

Translated title of the contributionSCHIZOBANK - The Hungarian national schizophrenia biobank and its role in schizophrenia research
Original languageHungarian
Pages (from-to)1403-1408
Number of pages6
JournalOrvosi Hetilap
Volume151
Issue number35
DOIs
StatePublished - Aug 1 2010
Externally publishedYes

Keywords

  • biobanking
  • database
  • personalized medicine
  • schizophrenia

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'SCHIZOBANK - The Hungarian national schizophrenia biobank and its role in schizophrenia research'. Together they form a unique fingerprint.

Cite this