TY - JOUR
T1 - Scatter, spatial resolution, and quantitative recovery in high resolution spect
AU - Szabo, Zsolt
AU - Links, Jonathan M.
AU - Seki, Chie
AU - Rhine, Jay
AU - Wagner, Henry N.
PY - 1992
Y1 - 1992
N2 - The potential use of single photon emission CT (SPECT) for quantification depends on its physical performance characteristics. We investigated the performance of a high resolution four-head brain SPECT scanner (Neuro-Spect; Summit/Hitachi). With an attenuation coefficient of 0.11 cm-1 and the Chang correction method, the calibration factor of the scanner was 515 (cpm/ ml)/(xCi/ml) and showed only a minimal but systematic dependence on object size. Without scatter, the resolution was 4.7 mm (full width at half-maximum); in a scatter medium, the resolution was 5.3-10.0 mm with high resolution collimation and 7.7-18.8 mm with general purpose collimation, depending on filtering. A recovery coefficient of close to 100% was measured in the center of spheres with a size of at least 20 mm placed in a cylindrical water-filled phantom. In lesions of this size, scatter was 20%. We conclude from our measurements that the investigated high resolution SPECT offers significant improvements in resolution, scatter, and recovery, which will improve both the quality of brain studies and the measurement of quantitative parameters such as the cortex/white matter ratio.
AB - The potential use of single photon emission CT (SPECT) for quantification depends on its physical performance characteristics. We investigated the performance of a high resolution four-head brain SPECT scanner (Neuro-Spect; Summit/Hitachi). With an attenuation coefficient of 0.11 cm-1 and the Chang correction method, the calibration factor of the scanner was 515 (cpm/ ml)/(xCi/ml) and showed only a minimal but systematic dependence on object size. Without scatter, the resolution was 4.7 mm (full width at half-maximum); in a scatter medium, the resolution was 5.3-10.0 mm with high resolution collimation and 7.7-18.8 mm with general purpose collimation, depending on filtering. A recovery coefficient of close to 100% was measured in the center of spheres with a size of at least 20 mm placed in a cylindrical water-filled phantom. In lesions of this size, scatter was 20%. We conclude from our measurements that the investigated high resolution SPECT offers significant improvements in resolution, scatter, and recovery, which will improve both the quality of brain studies and the measurement of quantitative parameters such as the cortex/white matter ratio.
KW - Spatial resolution-Scatter-Recovery-Quantification-Emission computed tomography
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U2 - 10.1097/00004728-199205000-00022
DO - 10.1097/00004728-199205000-00022
M3 - Article
C2 - 1592932
AN - SCOPUS:0026636942
SN - 0363-8715
VL - 16
SP - 461
EP - 467
JO - Journal of computer assisted tomography
JF - Journal of computer assisted tomography
IS - 3
ER -