Scatter, spatial resolution, and quantitative recovery in high resolution spect

Zsolt Szabo, Jonathan M. Links, Chie Seki, Jay Rhine, Henry N. Wagner

Research output: Contribution to journalArticle

Abstract

The potential use of single photon emission CT (SPECT) for quantification depends on its physical performance characteristics. We investigated the performance of a high resolution four-head brain SPECT scanner (Neuro-Spect; Summit/Hitachi). With an attenuation coefficient of 0.11 cm-1 and the Chang correction method, the calibration factor of the scanner was 515 (cpm/ ml)/(xCi/ml) and showed only a minimal but systematic dependence on object size. Without scatter, the resolution was 4.7 mm (full width at half-maximum); in a scatter medium, the resolution was 5.3-10.0 mm with high resolution collimation and 7.7-18.8 mm with general purpose collimation, depending on filtering. A recovery coefficient of close to 100% was measured in the center of spheres with a size of at least 20 mm placed in a cylindrical water-filled phantom. In lesions of this size, scatter was 20%. We conclude from our measurements that the investigated high resolution SPECT offers significant improvements in resolution, scatter, and recovery, which will improve both the quality of brain studies and the measurement of quantitative parameters such as the cortex/white matter ratio.

Original languageEnglish (US)
Pages (from-to)461-467
Number of pages7
JournalJournal of computer assisted tomography
Volume16
Issue number3
DOIs
StatePublished - Jan 1 1992

Keywords

  • Spatial resolution-Scatter-Recovery-Quantification-Emission computed tomography

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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