Scaling exponents of EEG are related to the temporal process of the therapeutic hypothermia following ischemic brain injury

Dineng Jiang; Wenqing Wu; Xiaofeng Jia; Yihong Qiu; Yisheng Zhu; Nitish Thakor; Shanbao Tong

doi:10.1109/IEMBS.2009.5334934

Scaling exponents of EEG are related to the temporal process of the therapeutic hypothermia following ischemic brain injury

Dineng Jiang, Wenqing Wu, Xiaofeng Jia, Yihong Qiu, Yisheng Zhu, Nitish Thakor, Shanbao Tong

School of Medicine

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Several markers based on quantitative electroencephalogram (qEEG) analysis have been associated with the neuroprotective effects of therapeutic hypothermia on hypoxicischemic encephalopathy (HIE) after cardiac arrest (CA). Nevertheless, the makers by far have not been linked to the temporal process of the ischemic neuronal death. In this study, we investigated the long-range correlations in EEG power in q and a bands before and after CA by detrended fluctuation analysis (DFA). The scaling components by DFA showed that the short-term scaling exponent in α band (i.e. γ^α ₁ ) was well correlated with recovery of brain injury during the latent phase. While the short-term scaling exponent in θ band (i.e. γθ₁ ) and the long-term scaling exponent in α band (i.e. γ^α₂) were correlated with the delayed neuronal death after CA. Our preliminary results showed that the long-range correlations in θ and α bands could be related the detail temporal process of therapeutic hypothermia.

Original language	English (US)
Title of host publication	Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Subtitle of host publication	Engineering the Future of Biomedicine, EMBC 2009
Publisher	IEEE Computer Society
Pages	2192-2195
Number of pages	4
ISBN (Print)	9781424432967
DOIs	https://doi.org/10.1109/IEMBS.2009.5334934
State	Published - Jan 1 2009
Event	31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009 - Minneapolis, MN, United States Duration: Sep 2 2009 → Sep 6 2009

Publication series

Name	Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009

Other

Other	31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009
Country	United States
City	Minneapolis, MN
Period	9/2/09 → 9/6/09

ASJC Scopus subject areas

Cell Biology
Developmental Biology
Biomedical Engineering
Medicine(all)

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Jiang, D., Wu, W., Jia, X., Qiu, Y., Zhu, Y., Thakor, N., & Tong, S. (2009). Scaling exponents of EEG are related to the temporal process of the therapeutic hypothermia following ischemic brain injury. In Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009 (pp. 2192-2195). [5334934] (Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009). IEEE Computer Society. https://doi.org/10.1109/IEMBS.2009.5334934

Scaling exponents of EEG are related to the temporal process of the therapeutic hypothermia following ischemic brain injury. / Jiang, Dineng; Wu, Wenqing; Jia, Xiaofeng; Qiu, Yihong; Zhu, Yisheng; Thakor, Nitish; Tong, Shanbao.

Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009. IEEE Computer Society, 2009. p. 2192-2195 5334934 (Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Jiang, D, Wu, W, Jia, X, Qiu, Y, Zhu, Y, Thakor, N & Tong, S 2009, Scaling exponents of EEG are related to the temporal process of the therapeutic hypothermia following ischemic brain injury. in Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009., 5334934, Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009, IEEE Computer Society, pp. 2192-2195, 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009, Minneapolis, MN, United States, 9/2/09. https://doi.org/10.1109/IEMBS.2009.5334934

Jiang D, Wu W, Jia X, Qiu Y, Zhu Y, Thakor N et al. Scaling exponents of EEG are related to the temporal process of the therapeutic hypothermia following ischemic brain injury. In Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009. IEEE Computer Society. 2009. p. 2192-2195. 5334934. (Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009). https://doi.org/10.1109/IEMBS.2009.5334934

Jiang, Dineng ; Wu, Wenqing ; Jia, Xiaofeng ; Qiu, Yihong ; Zhu, Yisheng ; Thakor, Nitish ; Tong, Shanbao. / Scaling exponents of EEG are related to the temporal process of the therapeutic hypothermia following ischemic brain injury. Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009. IEEE Computer Society, 2009. pp. 2192-2195 (Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009).

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abstract = "Several markers based on quantitative electroencephalogram (qEEG) analysis have been associated with the neuroprotective effects of therapeutic hypothermia on hypoxicischemic encephalopathy (HIE) after cardiac arrest (CA). Nevertheless, the makers by far have not been linked to the temporal process of the ischemic neuronal death. In this study, we investigated the long-range correlations in EEG power in q and a bands before and after CA by detrended fluctuation analysis (DFA). The scaling components by DFA showed that the short-term scaling exponent in α band (i.e. γα 1 ) was well correlated with recovery of brain injury during the latent phase. While the short-term scaling exponent in θ band (i.e. γθ1 ) and the long-term scaling exponent in α band (i.e. γα2) were correlated with the delayed neuronal death after CA. Our preliminary results showed that the long-range correlations in θ and α bands could be related the detail temporal process of therapeutic hypothermia.",

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