Scaling exponents of EEG are related to the temporal process of the therapeutic hypothermia following ischemic brain injury

Dineng Jiang, Wenqing Wu, Xiaofeng Jia, Yihong Qiu, Yisheng Zhu, Nitish Thakor, Shanbao Tong

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Several markers based on quantitative electroencephalogram (qEEG) analysis have been associated with the neuroprotective effects of therapeutic hypothermia on hypoxicischemic encephalopathy (HIE) after cardiac arrest (CA). Nevertheless, the makers by far have not been linked to the temporal process of the ischemic neuronal death. In this study, we investigated the long-range correlations in EEG power in q and a bands before and after CA by detrended fluctuation analysis (DFA). The scaling components by DFA showed that the short-term scaling exponent in α band (i.e. γα 1 ) was well correlated with recovery of brain injury during the latent phase. While the short-term scaling exponent in θ band (i.e. γθ1 ) and the long-term scaling exponent in α band (i.e. γα2) were correlated with the delayed neuronal death after CA. Our preliminary results showed that the long-range correlations in θ and α bands could be related the detail temporal process of therapeutic hypothermia.

Original languageEnglish (US)
Title of host publicationProceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Subtitle of host publicationEngineering the Future of Biomedicine, EMBC 2009
PublisherIEEE Computer Society
Pages2192-2195
Number of pages4
ISBN (Print)9781424432967
DOIs
StatePublished - Jan 1 2009
Event31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009 - Minneapolis, MN, United States
Duration: Sep 2 2009Sep 6 2009

Publication series

NameProceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009

Other

Other31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009
CountryUnited States
CityMinneapolis, MN
Period9/2/099/6/09

ASJC Scopus subject areas

  • Cell Biology
  • Developmental Biology
  • Biomedical Engineering
  • Medicine(all)

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