TY - JOUR
T1 - Scale-up of HIV treatment through PEPFAR
T2 - A historic public health achievement
AU - El-Sadr, Wafaa M.
AU - Holmes, Charles B.
AU - Mugyenyi, Peter
AU - Thirumurthy, Harsha
AU - Ellerbrock, Tedd
AU - Ferris, Robert
AU - Sanne, Ian
AU - Asiimwe, Anita
AU - Hirnschall, Gottfried
AU - Nkambule, Rejoice N.
AU - Stabinski, Lara
AU - Affrunti, Megan
AU - Teasdale, Chloe
AU - Zulu, Isaac
AU - Whiteside, Alan
PY - 2012/8/15
Y1 - 2012/8/15
N2 - Since its inception in 2003, the US President's Emergency Plan for AIDS Relief (PEPFAR) has been an important driving force behind the global scale-up of HIV care and treatment services, particularly in expansion of access to antiretroviral therapy. Despite initial concerns about cost and feasibility, PEPFAR overcame challenges by leveraging and coordinating with other funders, by working in partnership with the most affected countries, by supporting local ownership, by using a public health approach, by supporting task-shifting strategies, and by paying attention to health systems strengthening. As of September 2011, PEPFAR directly supported initiation of antiretroviral therapy for 3.9 million people and provided care and support for nearly 13 million people. Benefits in terms of prevention of morbidity and mortality have been reaped by those receiving the services, with evidence of societal benefits beyond the anticipated clinical benefits. However, much remains to be accomplished to achieve universal access, to enhance the quality of programs, to ensure retention of patients in care, and to continue to strengthen health systems.
AB - Since its inception in 2003, the US President's Emergency Plan for AIDS Relief (PEPFAR) has been an important driving force behind the global scale-up of HIV care and treatment services, particularly in expansion of access to antiretroviral therapy. Despite initial concerns about cost and feasibility, PEPFAR overcame challenges by leveraging and coordinating with other funders, by working in partnership with the most affected countries, by supporting local ownership, by using a public health approach, by supporting task-shifting strategies, and by paying attention to health systems strengthening. As of September 2011, PEPFAR directly supported initiation of antiretroviral therapy for 3.9 million people and provided care and support for nearly 13 million people. Benefits in terms of prevention of morbidity and mortality have been reaped by those receiving the services, with evidence of societal benefits beyond the anticipated clinical benefits. However, much remains to be accomplished to achieve universal access, to enhance the quality of programs, to ensure retention of patients in care, and to continue to strengthen health systems.
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U2 - 10.1097/QAI.0b013e31825eb27b
DO - 10.1097/QAI.0b013e31825eb27b
M3 - Article
C2 - 22797746
AN - SCOPUS:84866103737
SN - 1525-4135
VL - 60
SP - S96-S104
JO - Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology
JF - Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology
IS - SUPPL.3
ER -