TY - JOUR
T1 - Sarcomatous renal tumor in a child
T2 - A case report
AU - Sawada, Tadashi
AU - Tsunamoto, Kentaro
AU - Esumi, Noriko
AU - Morioka, Yoshihito
AU - Takeuchi, Yoshihiro
AU - Tanaka, Terufusa
AU - Kiyosawa, Nobuyuki
AU - Kusumoki, Tomoichi
N1 - Funding Information:
Received: July 9, 1982. This work was supported by a grant-in-aid for cancer research from the Ministry of Health and Welfare, Japan. Reprint requests: T. Sawada, M.D., Department of Pediatrics, Kyoto Prefectural University of Medicine, Kawara-machi, Kyoto 602, Japan.
Copyright:
Copyright 2010 Elsevier B.V., All rights reserved.
PY - 1982/12
Y1 - 1982/12
N2 - A patient, a 7-yr 4-mo-old boy, with sarcomatous renal tumor was presented. At the age of 3 yr and 1 mo, he had a right nephrectomy for a renal tumor, group I, which was histologically evaluated as an abortive subtype of the nephroblastic type of nephroblastoma. For 24 mo after surgery, the outlook for the patient seemed to be favorable. When he was 5 yr and 2 mo old, he complained of pain and swelling of the left shoulder. By X-ray examination, an osteolytic mass in the left scapula was discovered. After biopsy, it was histologically diagnosed as a metastasis of the sarcomatous renal tumor. During the next 29 mo, multiple bone metastases appeared in the ribs, vertebrae, skull and long bones and slowly increased in size.60Co irradiation of a total of 12,015 rads to four different regions and various chemotherapy regimens consisting of actinomycin D (AMD), AMD+vincristine (VCR), VCR+adriamycin (ADR)+cyclophosphamide (CYD), vinblastine+6-mercaptopurine and VCR+AMD+CYD, were given for the 53 mo from surgery to death, but they were not effective against this tumor.The clinical course of this case may show the natural history of sarcomatous renal tumor.
AB - A patient, a 7-yr 4-mo-old boy, with sarcomatous renal tumor was presented. At the age of 3 yr and 1 mo, he had a right nephrectomy for a renal tumor, group I, which was histologically evaluated as an abortive subtype of the nephroblastic type of nephroblastoma. For 24 mo after surgery, the outlook for the patient seemed to be favorable. When he was 5 yr and 2 mo old, he complained of pain and swelling of the left shoulder. By X-ray examination, an osteolytic mass in the left scapula was discovered. After biopsy, it was histologically diagnosed as a metastasis of the sarcomatous renal tumor. During the next 29 mo, multiple bone metastases appeared in the ribs, vertebrae, skull and long bones and slowly increased in size.60Co irradiation of a total of 12,015 rads to four different regions and various chemotherapy regimens consisting of actinomycin D (AMD), AMD+vincristine (VCR), VCR+adriamycin (ADR)+cyclophosphamide (CYD), vinblastine+6-mercaptopurine and VCR+AMD+CYD, were given for the 53 mo from surgery to death, but they were not effective against this tumor.The clinical course of this case may show the natural history of sarcomatous renal tumor.
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M3 - Article
AN - SCOPUS:77957210077
SN - 0368-2811
VL - 12
SP - 391
EP - 396
JO - Japanese Journal of Clinical Oncology
JF - Japanese Journal of Clinical Oncology
IS - 3
ER -