Sarcomas of bone in childhood: Pathologic aspects

J. M. Kissane, F. B. Askin, M. E. Nesbit, T. J. Vietti, E. O. Burgert, A. Cangir, E. A. Gehan, C. A. Perez, D. J. Pritchard, M. Tefft

Research output: Contribution to journalArticlepeer-review

Abstract

Some sarcomas of bone are not characteristically childhood tumors. Within the context of osteosarcomas, telangiectatic and parosteal (juxtacortical) variants deserve recognition. Among chondrosarcomas, which ordinarily are not tumors that occur in children, the mesenchymal variant should be recognized; in children especially, this lesion may be extraosseous. Fibrous histiocytoma and its malignant variant have recently emerged as morphologically specific lesions, occasionally osseous, among other spindle cell tumors. Ewing's sarcoma, which is predominantly of osseous origin, consists of undifferentiated fragile cells. The elaborate spectrum of topographic, cytologic, nuclear, and other morphologic features that fall within the designation Ewing's sarcoma are described.

Original languageEnglish (US)
Pages (from-to)29-41
Number of pages13
JournalNational Cancer Institute Monograph
VolumeNo. 56
StatePublished - 1981
Externally publishedYes

ASJC Scopus subject areas

  • Cancer Research

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