Same-day versus overnight observation after outpatient pediatric percutaneous liver biopsy

A retrospective cohort study

Svetlana Yuryevna Kozlovich, Anthony Alexander Sochet, Sorany Son, Michael Wilsey

Research output: Contribution to journalArticle

Abstract

Purpose: Percutaneous liver biopsy (PLB), a diagnostic procedure to identify several hepatobiliary disorders, is considered safe with low incidence of associated complications. While postoperative monitoring guidelines are suggested for adults, selection of procedural recovery time for children remains at the discretion of individual operators. We aim to determine if differences exist in frequency of surgical complications, unplanned admissions, and healthcare cost for children undergoing outpatient PLB for cohorts with same-day vs. overnight observation. Methods: We performed a retrospective cohort study in children 1 month to 17 years of age undergoing ultrasound-guided PLB from January 2009 to August 2017 at a tertiary care, pediatric referral center. Cohorts were defined by postprocedural observation duration: same-day (≤8 hours) vs. overnight observation. Outcomes included surgical complications, medical interventions, unscheduled hospitalization within 7 days, and total encounter costs. Results: One hundred and twelve children met study criteria of which 18 (16.1%) were assigned to same-day observation. No differences were noted in demographics, anthropometrics, comorbidities, biopsy indications, or preoperative coagulation profiles. No major complications or acute hospitalizations after PLB were observed. Administration of analgesia and fluid boluses were isolated and given within 8 hours. Compared to overnight monitoring, same-day observation accrued less total costs (US $992 less per encounter). Conclusion: Same-day observation after PLB in children appears well-tolerated with only minor interventions and complications observed within 8 hours of procedure. We recommend a targeted risk assessment prior to selection of observation duration. Same-day observation appears an appropriate recovery strategy in otherwise low-risk children undergoing outpatient PLB.

Original languageEnglish (US)
Pages (from-to)377-386
Number of pages10
JournalPediatric Gastroenterology, Hepatology and Nutrition
Volume22
Issue number4
DOIs
StatePublished - Jan 1 2019

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Cohort Studies
Outpatients
Retrospective Studies
Observation
Pediatrics
Biopsy
Liver
Hospitalization
Costs and Cost Analysis
Tertiary Healthcare
Health Care Costs
Analgesia
Comorbidity
Referral and Consultation
Demography
Guidelines
Incidence

Keywords

  • Biopsy
  • Complications
  • Cost effectiveness
  • Liver
  • Observation
  • Safety

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hepatology
  • Gastroenterology

Cite this

Same-day versus overnight observation after outpatient pediatric percutaneous liver biopsy : A retrospective cohort study. / Kozlovich, Svetlana Yuryevna; Sochet, Anthony Alexander; Son, Sorany; Wilsey, Michael.

In: Pediatric Gastroenterology, Hepatology and Nutrition, Vol. 22, No. 4, 01.01.2019, p. 377-386.

Research output: Contribution to journalArticle

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