Sam68 Offers Selectively Aimed Modulation of Transcription in Cancer Stem Cells

Kai Fu, Fengyi Wan

Research output: Research - peer-reviewShort survey

Abstract

In this issue of Cell Chemical Biology, Benoit et al. (2017) report the selective targeting of cancer stem cells (CSCs) by the ICG-001/CWP family of molecules. Their findings reveal that Sam68 is a transcriptional modulator uniquely required for the dysregulated Wnt/β-catenin signaling in CSCs over healthy stem cells.

LanguageEnglish (US)
Pages777-779
Number of pages3
JournalCell Chemical Biology
Volume24
Issue number7
DOIs
StatePublished - Jul 20 2017

Fingerprint

Transcription
Stem cells
Modulation
Neoplastic Stem Cells
beta Catenin
Cell Biology
Stem Cells
ICG 001
Modulators
Molecules

ASJC Scopus subject areas

  • Biochemistry
  • Clinical Biochemistry
  • Molecular Biology
  • Molecular Medicine
  • Drug Discovery
  • Pharmacology

Cite this

Sam68 Offers Selectively Aimed Modulation of Transcription in Cancer Stem Cells. / Fu, Kai; Wan, Fengyi.

In: Cell Chemical Biology, Vol. 24, No. 7, 20.07.2017, p. 777-779.

Research output: Research - peer-reviewShort survey

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