Sam68 Offers Selectively Aimed Modulation of Transcription in Cancer Stem Cells

Kai Fu, Fengyi Wan

Research output: Contribution to journalShort surveypeer-review

Abstract

In this issue of Cell Chemical Biology, Benoit et al. (2017) report the selective targeting of cancer stem cells (CSCs) by the ICG-001/CWP family of molecules. Their findings reveal that Sam68 is a transcriptional modulator uniquely required for the dysregulated Wnt/β-catenin signaling in CSCs over healthy stem cells.

Original languageEnglish (US)
Pages (from-to)777-779
Number of pages3
JournalCell Chemical Biology
Volume24
Issue number7
DOIs
StatePublished - Jul 20 2017

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmacology
  • Drug Discovery
  • Clinical Biochemistry

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