Salivary gland development in Drosophila melanogaster

Deborah J. Andrew; Katya D. Henderson; Partha Seshaiah

doi:10.1016/S0925-4773(99)00321-4

Salivary gland development in Drosophila melanogaster

Deborah J. Andrew, Katya D. Henderson, Partha Seshaiah

School of Medicine

Research output: Contribution to journal › Review article

Abstract

The Drosophila salivary gland is proving to be an excellent experimental system for understanding how cells commit to specific developmental programs and, once committed, how cells implement such decisions. Through genetic studies, the factors that determine where salivary glands will form, the number of cells committed to a salivary gland fate, and the distinction between the two major cell types (secretory cells and duct cells) have been discovered. Within the next few years, we will learn the molecular details of the interactions among the salivary gland regulators and salivary gland target genes. We will also learn how the early-expressed salivary gland genes coordinate their activities to mediate the morphogenetic movements required to form the salivary gland and the changes in cell physiology required for high secretory activity. (C) 2000 Elsevier Science Ireland Ltd.

Original language	English (US)
Pages (from-to)	5-17
Number of pages	13
Journal	Mechanisms of Development
Volume	92
Issue number	1
DOIs	https://doi.org/10.1016/S0925-4773(99)00321-4
State	Published - Mar 15 2000

Keywords

DPP-signaling
Drosophila
EGF-signaling
Extradenticle
Fork head
Homothorax
Salivary gland
Sex combs reduced
Trachealess

ASJC Scopus subject areas

Embryology
Developmental Biology

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Andrew, D. J., Henderson, K. D., & Seshaiah, P. (2000). Salivary gland development in Drosophila melanogaster. Mechanisms of Development, 92(1), 5-17. https://doi.org/10.1016/S0925-4773(99)00321-4

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