Salicylic acid and analogues as diaCEST MRI contrast agents with highly shifted exchangeable proton frequencies

Xing Yang, Xiaolei Song, Yuguo Li, Guanshu Liu, Sangeeta Ray Banerjee, Martin G. Pomper, Michael T. McMahon

Research output: Contribution to journalArticlepeer-review

58 Scopus citations

Abstract

More than water: Chemical exchange saturation transfer (CEST) contrast agents have used water bound to lanthanides as a source of highly shifted exchangeable proton frequencies. Compounds with the 2-hydroxybenzoic acid scaffold were investigated as a source of highly shifted protons for CEST MRI contrasting.

Original languageEnglish (US)
Pages (from-to)8116-8119
Number of pages4
JournalAngewandte Chemie - International Edition
Volume52
Issue number31
DOIs
StatePublished - Jul 29 2013

Keywords

  • CEST imaging
  • contrast agents
  • magnetic resonance imaging
  • molecular imaging
  • salicylic acid

ASJC Scopus subject areas

  • Catalysis
  • General Chemistry

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