Safety of trazodone as a sleep agent for inpatients

Geetha Jayaram, Pravin Rao

Research output: Contribution to journalLetter

Abstract

Trazodone, an atypical antidepressant with relatively low anticholinergic and cardiac conduction effects, offers useful augmentation to classic antidepressant drugs, notably selective serotonin reuptake inhibitors. One rare but serious side effect of the drug is priapism, the urological emergency in which the cavemosa of the penis become painfully engorged in the absence of sexual stimulation. The authors present what appears to be the first published case of priapism requiring urologic intervention after a single 100-mg dose of trazodone. In addition to a discussion of the history and physiology of trazodone and priapism, the authors present a profile of patients who present a safety risk in treatment.

Original languageEnglish (US)
Pages (from-to)367-369
Number of pages3
JournalPsychosomatics
Volume46
Issue number4
DOIs
StatePublished - Jan 1 2005

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Applied Psychology
  • Psychiatry and Mental health

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