Safety and efficacy of MD1003 (high-dose biotin) in patients with progressive multiple sclerosis (SPI2): a randomised, double-blind, placebo-controlled, phase 3 trial

Bruce A.C. Cree, Gary Cutter, Jerry S. Wolinsky, Mark S. Freedman, Giancarlo Comi, Gavin Giovannoni, Hans Peter Hartung, Douglas Arnold, Jens Kuhle, Valerie Block, Frederick E. Munschauer, Frédéric Sedel, Fred D. Lublin, Stephen Reingold, Pierre Duquette, Tobias Derfuss, Franz Fazekas, Maria Pia Sormani, Robert P. Lisak, Jennifer GravesStephen Krieger, Rana K. Zabad, Scott Newsome, Joshua Barton, Richard MacDonell, Mark Marriott, Nina De Klippel, Guy Laureys, Barbara Willekens, Virginia Devonshire, Mark Freedman, J. Marc Girard, Paul Giacomini, Roger McKelvey, Daniel Selchen, Galina Vorobeychik, Ludivine Witkowski, Radek Ampapa, Jana Lizrova Preiningerova, Eva Meluzinova, Radomir Talab, Marta Vachova, Orhan Aktas, Mathias Buttmann, Elias Hamp Birte, Tania Kuempfel, Paul Friedemann, Daniela Rau, Gerd Reifschneider, Piotr Sokolowski, Hayrettin Tumani, Maria Satori, Carlo Pozzilli, Agata Klosek, Jozef Koscielniak, Fryze Waldemar, Malgorzata Zajda, Rafael Arroyo Gonzalez, Guillermo Izquierdo Ayuso, Victoria Fernandez Sanchez, Celia Oreja Guevara, Jose Enrique Martinez Rodriguez, Xavier Montalban, Lluis Ramio-Torrenta, Lou Brundin, Jan Lycke, Murat Terzi, Joe Guadagno, Don Mahad, Adrian Pace, Klaus Schmierer, Ahmed Toosy, Stewart Webb, Mark Agius, Lilyana Amezcua, Michelle Apperson, Bridget Bagert, Daniel Bandari, Evanthia Bernitsas, Jonathan Calkwood, Jonathan Carter, Bruce Cohen, Devon Conway, Joanna Cooper, John Corboy, Patricia Coyle, Bruce Cree, Mitchel Freedman, Corey Ford, Edward Fox, Myla Goldman, Benjamin Greenberg, Mariko Kita, Thomas Leist, Sharon Lynch, Aaron Miller, Harold Moses, Robert Naismith, Mary Ann Picone, Bhatia Perminder, Alexander Rae-Grant, Kottil Rammohan, Anthony Reder, Claire Riley, Derrick Robertson, Vernon Rowe, Shiv Saidha, Lawrence Samkoff, Christopher Severson, Kyle Smoot, Sharon Stoll, Randall Trudell, Bianca Weinstock-Guttman, Sanjay Yathiraj

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