Safety and efficacy of low-dose esterified estrogens and methyltestosterone, alone or combined, for the treatment of hot flashes in menopausal women: A randomized, double-blind, placebo-controlled study

James Liu; Adam Allgood; Leonard R. Derogatis; Stephen Swanson; Michael O'Mahony; Bertrand Nedoss; Herbert Soper; Edward Zbella; Svetlana Vladimirovna Prokofieva; Lisa Zipfel; Chun Yuan Guo

doi:10.1016/j.fertnstert.2010.08.005

Safety and efficacy of low-dose esterified estrogens and methyltestosterone, alone or combined, for the treatment of hot flashes in menopausal women: A randomized, double-blind, placebo-controlled study

James Liu, Adam Allgood, Leonard R. Derogatis, Stephen Swanson, Michael O'Mahony, Bertrand Nedoss, Herbert Soper, Edward Zbella, Svetlana Vladimirovna Prokofieva, Lisa Zipfel, Chun Yuan Guo

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

This study evaluated safety and efficacy of esterified estrogens and methyltestosterone administered alone or in combination for the treatment of hot flashes in menopausal women. The 0.30-mg esterified estrogens and 0.30-mg methyltestosterone combination was the lowest effective dose, and our results are consistent with the known safety profile of estrogen and androgen combination products.

Original language	English (US)
Pages (from-to)	366-368
Number of pages	3
Journal	Fertility and sterility
Volume	95
Issue number	1
DOIs	https://doi.org/10.1016/j.fertnstert.2010.08.005
State	Published - Jan 2011
Externally published	Yes

Keywords

Postmenopausal women
esterified estrogens (EE)
hormone replacement therapy
hot flashes
lowest effective dose
methyltestosterone (MT)
vasomotor symptoms

ASJC Scopus subject areas

Reproductive Medicine
Obstetrics and Gynecology

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10.1016/j.fertnstert.2010.08.005

Cite this

Liu, J., Allgood, A., Derogatis, L. R., Swanson, S., O'Mahony, M., Nedoss, B., Soper, H., Zbella, E., Prokofieva, S. V., Zipfel, L., & Guo, C. Y. (2011). Safety and efficacy of low-dose esterified estrogens and methyltestosterone, alone or combined, for the treatment of hot flashes in menopausal women: A randomized, double-blind, placebo-controlled study. Fertility and sterility, 95(1), 366-368. https://doi.org/10.1016/j.fertnstert.2010.08.005

Safety and efficacy of low-dose esterified estrogens and methyltestosterone, alone or combined, for the treatment of hot flashes in menopausal women: A randomized, double-blind, placebo-controlled study. / Liu, James; Allgood, Adam; Derogatis, Leonard R. et al.
In: Fertility and sterility, Vol. 95, No. 1, 01.2011, p. 366-368.

Research output: Contribution to journal › Article › peer-review

Liu, J, Allgood, A, Derogatis, LR, Swanson, S, O'Mahony, M, Nedoss, B, Soper, H, Zbella, E, Prokofieva, SV, Zipfel, L & Guo, CY 2011, 'Safety and efficacy of low-dose esterified estrogens and methyltestosterone, alone or combined, for the treatment of hot flashes in menopausal women: A randomized, double-blind, placebo-controlled study', Fertility and sterility, vol. 95, no. 1, pp. 366-368. https://doi.org/10.1016/j.fertnstert.2010.08.005

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Safety and efficacy of low-dose esterified estrogens and methyltestosterone, alone or combined, for the treatment of hot flashes in menopausal women: A randomized, double-blind, placebo-controlled study

Abstract

Keywords

ASJC Scopus subject areas

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