Saccharomyces boulardii probiotic-associated fungemia: questioning the safety of this preventive probiotic's use

Isabella W. Martin, Rita Tonner, Julie Trivedi, Heather Miller, Richard Lee, Xinglun Liang, Leo Rotello, Elena Isenbergh, Jennifer Anderson, Trish Perl, Sean Xiang Zhang

Research output: Contribution to journalArticle

Abstract

We report a case of fungemia in an immunocompetent patient after administration of probiotic containing Saccharomyces boulardii. We demonstrated the strain relatedness of the yeast from the probiotic capsule and the yeast causing fungal infection using genomic and proteomic typing methods. Our study questions the safety of this preventative biotherapy.

Original languageEnglish (US)
Pages (from-to)286-288
Number of pages3
JournalDiagnostic Microbiology and Infectious Disease
Volume87
Issue number3
DOIs
StatePublished - Mar 1 2017

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Fungemia
Probiotics
Yeasts
Safety
Biological Therapy
Mycoses
Proteomics
Capsules
Saccharomyces boulardii

Keywords

  • Fungal infection
  • Fungemia
  • Probiotic
  • Saccharomyces boulardii
  • Strain typing

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Cite this

Saccharomyces boulardii probiotic-associated fungemia : questioning the safety of this preventive probiotic's use. / Martin, Isabella W.; Tonner, Rita; Trivedi, Julie; Miller, Heather; Lee, Richard; Liang, Xinglun; Rotello, Leo; Isenbergh, Elena; Anderson, Jennifer; Perl, Trish; Zhang, Sean Xiang.

In: Diagnostic Microbiology and Infectious Disease, Vol. 87, No. 3, 01.03.2017, p. 286-288.

Research output: Contribution to journalArticle

Martin, Isabella W. ; Tonner, Rita ; Trivedi, Julie ; Miller, Heather ; Lee, Richard ; Liang, Xinglun ; Rotello, Leo ; Isenbergh, Elena ; Anderson, Jennifer ; Perl, Trish ; Zhang, Sean Xiang. / Saccharomyces boulardii probiotic-associated fungemia : questioning the safety of this preventive probiotic's use. In: Diagnostic Microbiology and Infectious Disease. 2017 ; Vol. 87, No. 3. pp. 286-288.
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