Russell bodies and plasma cells in human conjunctiva

Harry A. Quigley, Kenneth R. Kenyon

Research output: Contribution to journalArticle

Abstract

Conjunctival biopsies from patients with systemic mucopolysaccharidoses and macular corneal dystrophy and from normal subjects were examined histologically and ultrastructurally. In the subepithelial connective tissue, plasma cells were commonly present, which were usually unassociated with other inflammatory cells. In several cases, plasma cells exhibited Russell bodies as large, electrondense inclusions within dilated cisternae of rough-surfaced endoplasmic reticulum. The association of these cells with specific diseases and their histopathologic significance remains unclear, but the possibility that conjunctival plasma cells and Russell bodies are components of a localized secretory immune system exists.

Original languageEnglish (US)
Pages (from-to)957-966
Number of pages10
JournalAmerican journal of ophthalmology
Volume76
Issue number6
DOIs
StatePublished - Dec 1973

ASJC Scopus subject areas

  • Ophthalmology

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