Rural–urban disparities in colorectal cancer survival and risk among men in Utah: a statewide population-based study

Charles R. Rogers, Brenna E. Blackburn, Matthew Huntington, Karen Curtin, Roland J. Thorpe, Kerry Rowe, John Snyder, Vikrant Deshmukh, Michael Newman, Alison Fraser, Ken Smith, Mia Hashibe

Research output: Contribution to journalArticle

Abstract

Rural areas of the U.S. experience disproportionate colorectal cancer (CRC) death compared to urban areas. The authors aimed to analyze differences in CRC survival between rural and urban Utah men and investigate potential prognostic factors for survival among these men. A cohort of Utah men diagnosed with CRC between 1997 and 2013 was identified from the Utah Cancer Registry. Survival and prognostic factors were analyzed via 5-year CRC survival and Cox proportional hazards models, stratified by rural/urban residence. Among 4,660 men diagnosed with CRC, 15.3% were living in rural Utah. Compared with urban men, rural CRC patients were diagnosed at older ages and in different anatomic subsites; more were overweight, and current smokers. Differences in stage and treatment were not apparent between rural and urban CRC patients. Compared with urban counterparts, rural men experienced a lower CRC survival (Hazard Ratio 0.55, 95% CI 0.53, 0.58 vs. 0.58, 95% CI 0.56, 0.59). Race and cancer treatment influenced CRC survival among men living in both urban and rural areas. Factors of CRC survival varied greatly among urban and rural men in Utah. The influence of social and environmental conditions on health behaviors and outcomes merits further exploration.

Original languageEnglish (US)
Pages (from-to)241-253
Number of pages13
JournalCancer Causes and Control
Volume31
Issue number3
DOIs
StatePublished - Mar 1 2020

Keywords

  • Colonic neoplasms
  • Health status disparities
  • Men’s health
  • Rural health
  • Survival
  • Urban health

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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  • Cite this

    Rogers, C. R., Blackburn, B. E., Huntington, M., Curtin, K., Thorpe, R. J., Rowe, K., Snyder, J., Deshmukh, V., Newman, M., Fraser, A., Smith, K., & Hashibe, M. (2020). Rural–urban disparities in colorectal cancer survival and risk among men in Utah: a statewide population-based study. Cancer Causes and Control, 31(3), 241-253. https://doi.org/10.1007/s10552-020-01268-2