RSPECT

A compact gamma camera based spect system for small-animal imaging

Eduardo Lage, José L. Villena, Gustavo Tapias, I. Vidal-Migallón, Mónica Abella, Alejandro Sisniega Crespo, Naira P. Martínez, Doménec Ros, Manuel Desco, Juan J. Vaquero

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We have developed a compact and modular gamma camera system and assessed its performance when used on a small-animal SPECT prototype (rSPECT). Each camera consists of a Hamamatsu H-8500 position sensitive photomultiplier tube coupled to a 30 x 30 NaI (Tl) scintillator array (1.4mm x 1.4mm x 6mm crystal size) and electronics for pre-processing and matching the detector signals to an in-house developed data acquisition system. The camera components are enclosed in a lead-shielded case with a receptacle to insert the collimators (parallel-hole or pinhole with different tungsten apertures). System performance has been assessed for a low energy high resolution parallel-hole collimator (LEHR), and for a 0.75 mm pinhole collimator with 60° aperture angle. In this paper we present details on the system implementation and results of performance measurements, as well as first tomographic images on phantoms and animals. This SPECT was conceived for compactness and cost-effective routine small-animal imaging, and acquisitions of living mice and rats carried out with the system demonstrate its ability to provide useful high-resolution images for in vivo research. Index Terms - Single Photon Emission Computed Tomography (SPECT), small-animal imaging, gamma camera.

Original languageEnglish (US)
Title of host publication2009 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2009
Pages3126-3131
Number of pages6
DOIs
StatePublished - Dec 1 2009
Externally publishedYes
Event2009 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2009 - Orlando, FL, United States
Duration: Oct 25 2009Oct 31 2009

Other

Other2009 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2009
CountryUnited States
CityOrlando, FL
Period10/25/0910/31/09

Fingerprint

Gamma Cameras
animals
collimators
Single-Photon Emission-Computed Tomography
cameras
tomography
pinholes
photons
apertures
signal detectors
Tungsten
high resolution
void ratio
photomultiplier tubes
preprocessing
inserts
containers
Information Systems
Radionuclide Imaging
scintillation counters

ASJC Scopus subject areas

  • Radiation
  • Nuclear and High Energy Physics
  • Radiology Nuclear Medicine and imaging

Cite this

Lage, E., Villena, J. L., Tapias, G., Vidal-Migallón, I., Abella, M., Sisniega Crespo, A., ... Vaquero, J. J. (2009). RSPECT: A compact gamma camera based spect system for small-animal imaging. In 2009 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2009 (pp. 3126-3131). [5401682] https://doi.org/10.1109/NSSMIC.2009.5401682

RSPECT : A compact gamma camera based spect system for small-animal imaging. / Lage, Eduardo; Villena, José L.; Tapias, Gustavo; Vidal-Migallón, I.; Abella, Mónica; Sisniega Crespo, Alejandro; Martínez, Naira P.; Ros, Doménec; Desco, Manuel; Vaquero, Juan J.

2009 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2009. 2009. p. 3126-3131 5401682.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Lage, E, Villena, JL, Tapias, G, Vidal-Migallón, I, Abella, M, Sisniega Crespo, A, Martínez, NP, Ros, D, Desco, M & Vaquero, JJ 2009, RSPECT: A compact gamma camera based spect system for small-animal imaging. in 2009 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2009., 5401682, pp. 3126-3131, 2009 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2009, Orlando, FL, United States, 10/25/09. https://doi.org/10.1109/NSSMIC.2009.5401682
Lage E, Villena JL, Tapias G, Vidal-Migallón I, Abella M, Sisniega Crespo A et al. RSPECT: A compact gamma camera based spect system for small-animal imaging. In 2009 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2009. 2009. p. 3126-3131. 5401682 https://doi.org/10.1109/NSSMIC.2009.5401682
Lage, Eduardo ; Villena, José L. ; Tapias, Gustavo ; Vidal-Migallón, I. ; Abella, Mónica ; Sisniega Crespo, Alejandro ; Martínez, Naira P. ; Ros, Doménec ; Desco, Manuel ; Vaquero, Juan J. / RSPECT : A compact gamma camera based spect system for small-animal imaging. 2009 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2009. 2009. pp. 3126-3131
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