Rotavirus diarrhoea: An expanding clinical spectrum

J. D. Clemens, M. Ahmed, T. Butler, W. B. Greenough, D. A. Sack, B. F. Stanton

Research output: Contribution to journalArticlepeer-review

Abstract

To explore the cinical spectrum of rotavirus diarrhoea in Bangladeshi children, we reviewed surveillance data from randomly selected diarrhoeal cases who were intensively studied at the Internatonal Centre for Diarrhoeal Diseases Research - Babgladesh. Twenty-seven (29%) of children aged ≤4 years excreted rotavirus; rotavirus was the only pathogen isolated from 13 cases. Seven of these 13 cases displayed the typical features of rotavirus diarrhoea: occurrence in infancy, prominent vomiting, watery diarrhoea, and acidic stools rarely exhibiting blood or leucocytes. In contrast, 6 of the 13 cases presented with non-watery diarrhoea. These cases were distinguished by older ages, infrequent vomiting, less acidic stools, faecal blood and leucocytes, and frequent left shifts on peripheral blood examination. We conclude that the clinical spectrum of rotavirus infections may include an invasive diarrhoeal syndrome that differs in several respects from the more widely appreciated watery diarrhoeal syndrome.

Original languageEnglish (US)
Pages (from-to)117-122
Number of pages6
JournalJournal of Tropical Medicine and Hygiene
Volume86
Issue number3
StatePublished - Dec 1 1983
Externally publishedYes

ASJC Scopus subject areas

  • Parasitology
  • Environmental Science(all)
  • Engineering(all)
  • Infectious Diseases
  • Earth and Planetary Sciences(all)

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