TY - JOUR
T1 - Room-specific characteristics of suburban homes as predictors of indoor allergen concentrations
AU - Perry, Tamara T.
AU - Wood, Robert A.
AU - Matsui, Elizabeth C.
AU - Curtin-Brosnan, Jean
AU - Rand, Cynthia
AU - Eggleston, Peyton A.
N1 - Funding Information:
* Department of Pediatrics, Division of Allergy and Immunology, University of Arkansas for Medical Sciences College of Medicine, Little Rock, Arkansas. † Department of Pediatrics, Eudowood Division of Immunology and Allergy, Johns Hopkins University School of Medicine, Baltimore, Maryland. ‡ Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland. The study was funded by NHLBI R18-HL058942, NIEHS P01ES09606, and US Environmental Protection Agency R-82672401. Received for publication February 24, 2006. Accepted for publication in revised form May 21, 2006.
PY - 2006/11
Y1 - 2006/11
N2 - Background: Room characteristics predicting indoor allergen exposure in suburban homes have not been clearly identified. Objective: To examine relationships between room characteristics and concentrations of indoor allergens in homes of suburban asthmatic patients. Methods: The homes of 339 asthmatic children ages 6 to 17 years were studied. Home inspections were conducted by a trained technician, and dust samples were analyzed for indoor allergen content. A high allergen concentration was defined as 8 μg (U)/g or more of fine dust. Results: Infrequent sheet washing and wall-to-wall carpet were risk factors for high bedroom dust mite concentrations. Infrequent sheet washing was also a risk factor for high Fel d l concentrations. Food remains in the bedroom was a risk factor for high bedroom Bla g l levels, and exposed food, leaks, and dirty pots were all risk factors for high kitchen Bla g l levels. The combination of lack of mattress or pillow encasements, infrequent sheet washing, and carpeting was associated with a 24-fold increase in odds of a high dust mite concentration (odds ratio [OR], 24.1; 95% confidence interval [CI], 3.2-181.4). Among non-cat owners, the combination of stuffed toys on the bed, lack of mattress or pillow encasements, and infrequent sheet washing was associated with a 49-fold increase in odds of a high Pel d l level (OR, 49.4; 95% CI, 2.8-887.3). The combination of leaks, exposed food, and dirty pots was associated with a high kitchen Bla g l concentration (OR, 10.6; 95% CI, 2.8-40.5). Conclusions: Specific room characteristics predict high indoor allergen exposure among children with asthma, and a combination of these characteristics may further increase the risk of high allergen exposure.
AB - Background: Room characteristics predicting indoor allergen exposure in suburban homes have not been clearly identified. Objective: To examine relationships between room characteristics and concentrations of indoor allergens in homes of suburban asthmatic patients. Methods: The homes of 339 asthmatic children ages 6 to 17 years were studied. Home inspections were conducted by a trained technician, and dust samples were analyzed for indoor allergen content. A high allergen concentration was defined as 8 μg (U)/g or more of fine dust. Results: Infrequent sheet washing and wall-to-wall carpet were risk factors for high bedroom dust mite concentrations. Infrequent sheet washing was also a risk factor for high Fel d l concentrations. Food remains in the bedroom was a risk factor for high bedroom Bla g l levels, and exposed food, leaks, and dirty pots were all risk factors for high kitchen Bla g l levels. The combination of lack of mattress or pillow encasements, infrequent sheet washing, and carpeting was associated with a 24-fold increase in odds of a high dust mite concentration (odds ratio [OR], 24.1; 95% confidence interval [CI], 3.2-181.4). Among non-cat owners, the combination of stuffed toys on the bed, lack of mattress or pillow encasements, and infrequent sheet washing was associated with a 49-fold increase in odds of a high Pel d l level (OR, 49.4; 95% CI, 2.8-887.3). The combination of leaks, exposed food, and dirty pots was associated with a high kitchen Bla g l concentration (OR, 10.6; 95% CI, 2.8-40.5). Conclusions: Specific room characteristics predict high indoor allergen exposure among children with asthma, and a combination of these characteristics may further increase the risk of high allergen exposure.
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U2 - 10.1016/S1081-1206(10)61092-7
DO - 10.1016/S1081-1206(10)61092-7
M3 - Article
C2 - 17165271
AN - SCOPUS:33845192650
SN - 1081-1206
VL - 97
SP - 628
EP - 635
JO - Annals of Allergy, Asthma and Immunology
JF - Annals of Allergy, Asthma and Immunology
IS - 5
ER -