Role of the thalamus in parkinsonian tremor: Evidence from studies in patients and primate models

Frederick Lenz, J. L. Vitek, M. R. DeLong

Research output: Contribution to journalArticle

Abstract

The electrophysiologic basis of parkinsonian tremor is discussed in terms of the central oscillator and peripheral feedback hypotheses of tremor. Recent studies in monkeys and humans suggest that parkinsonian tremor may result from the activity of a central oscillator, possibly located in the basal ganglia. Peripheral somatosensory input seems to modulate tremor and central nervous system activity related to tremor.

Original languageEnglish (US)
Pages (from-to)94-103
Number of pages10
JournalStereotactic and Functional Neurosurgery
Volume60
Issue number1-3
DOIs
StatePublished - 1993

Fingerprint

Tremor
Thalamus
Primates
Basal Ganglia
Haplorhini
Central Nervous System

Keywords

  • Basal ganglia
  • Feedback processes
  • Neuronal oscillators
  • Parkinson’s disease
  • Thalamus
  • Tremor

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

Role of the thalamus in parkinsonian tremor : Evidence from studies in patients and primate models. / Lenz, Frederick; Vitek, J. L.; DeLong, M. R.

In: Stereotactic and Functional Neurosurgery, Vol. 60, No. 1-3, 1993, p. 94-103.

Research output: Contribution to journalArticle

@article{3bd29eb25d8b4393a0fe784bf969ca04,
title = "Role of the thalamus in parkinsonian tremor: Evidence from studies in patients and primate models",
abstract = "The electrophysiologic basis of parkinsonian tremor is discussed in terms of the central oscillator and peripheral feedback hypotheses of tremor. Recent studies in monkeys and humans suggest that parkinsonian tremor may result from the activity of a central oscillator, possibly located in the basal ganglia. Peripheral somatosensory input seems to modulate tremor and central nervous system activity related to tremor.",
keywords = "Basal ganglia, Feedback processes, Neuronal oscillators, Parkinson’s disease, Thalamus, Tremor",
author = "Frederick Lenz and Vitek, {J. L.} and DeLong, {M. R.}",
year = "1993",
doi = "10.1159/000100595",
language = "English (US)",
volume = "60",
pages = "94--103",
journal = "Stereotactic and Functional Neurosurgery",
issn = "1011-6125",
publisher = "S. Karger AG",
number = "1-3",

}

TY - JOUR

T1 - Role of the thalamus in parkinsonian tremor

T2 - Evidence from studies in patients and primate models

AU - Lenz, Frederick

AU - Vitek, J. L.

AU - DeLong, M. R.

PY - 1993

Y1 - 1993

N2 - The electrophysiologic basis of parkinsonian tremor is discussed in terms of the central oscillator and peripheral feedback hypotheses of tremor. Recent studies in monkeys and humans suggest that parkinsonian tremor may result from the activity of a central oscillator, possibly located in the basal ganglia. Peripheral somatosensory input seems to modulate tremor and central nervous system activity related to tremor.

AB - The electrophysiologic basis of parkinsonian tremor is discussed in terms of the central oscillator and peripheral feedback hypotheses of tremor. Recent studies in monkeys and humans suggest that parkinsonian tremor may result from the activity of a central oscillator, possibly located in the basal ganglia. Peripheral somatosensory input seems to modulate tremor and central nervous system activity related to tremor.

KW - Basal ganglia

KW - Feedback processes

KW - Neuronal oscillators

KW - Parkinson’s disease

KW - Thalamus

KW - Tremor

UR - http://www.scopus.com/inward/record.url?scp=0027159156&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027159156&partnerID=8YFLogxK

U2 - 10.1159/000100595

DO - 10.1159/000100595

M3 - Article

C2 - 8511438

AN - SCOPUS:0027159156

VL - 60

SP - 94

EP - 103

JO - Stereotactic and Functional Neurosurgery

JF - Stereotactic and Functional Neurosurgery

SN - 1011-6125

IS - 1-3

ER -