Role of the thalamus in parkinsonian tremor: Evidence from studies in patients and primate models

F. A. Lenz; J. L. Vitek; M. R. DeLong

doi:10.1159/000100595

Role of the thalamus in parkinsonian tremor: Evidence from studies in patients and primate models

F. A. Lenz, J. L. Vitek, M. R. DeLong

School of Medicine

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Abstract

The electrophysiologic basis of parkinsonian tremor is discussed in terms of the central oscillator and peripheral feedback hypotheses of tremor. Recent studies in monkeys and humans suggest that parkinsonian tremor may result from the activity of a central oscillator, possibly located in the basal ganglia. Peripheral somatosensory input seems to modulate tremor and central nervous system activity related to tremor.

Original language	English (US)
Pages (from-to)	94-103
Number of pages	10
Journal	Stereotactic and Functional Neurosurgery
Volume	60
Issue number	1-3
DOIs	https://doi.org/10.1159/000100595
State	Published - 1993

Keywords

Basal ganglia
Feedback processes
Neuronal oscillators
Parkinson’s disease
Thalamus
Tremor

ASJC Scopus subject areas

Surgery
Clinical Neurology

Access to Document

10.1159/000100595

Cite this

@article{3bd29eb25d8b4393a0fe784bf969ca04,

title = "Role of the thalamus in parkinsonian tremor: Evidence from studies in patients and primate models",

abstract = "The electrophysiologic basis of parkinsonian tremor is discussed in terms of the central oscillator and peripheral feedback hypotheses of tremor. Recent studies in monkeys and humans suggest that parkinsonian tremor may result from the activity of a central oscillator, possibly located in the basal ganglia. Peripheral somatosensory input seems to modulate tremor and central nervous system activity related to tremor.",

keywords = "Basal ganglia, Feedback processes, Neuronal oscillators, Parkinson{\textquoteright}s disease, Thalamus, Tremor",

author = "Lenz, {F. A.} and Vitek, {J. L.} and DeLong, {M. R.}",

year = "1993",

doi = "10.1159/000100595",

language = "English (US)",

volume = "60",

pages = "94--103",

journal = "Stereotactic and Functional Neurosurgery",

issn = "1011-6125",

publisher = "S. Karger AG",

number = "1-3",

}

TY - JOUR

T1 - Role of the thalamus in parkinsonian tremor

T2 - Evidence from studies in patients and primate models

AU - Lenz, F. A.

AU - Vitek, J. L.

AU - DeLong, M. R.

PY - 1993

Y1 - 1993

N2 - The electrophysiologic basis of parkinsonian tremor is discussed in terms of the central oscillator and peripheral feedback hypotheses of tremor. Recent studies in monkeys and humans suggest that parkinsonian tremor may result from the activity of a central oscillator, possibly located in the basal ganglia. Peripheral somatosensory input seems to modulate tremor and central nervous system activity related to tremor.

AB - The electrophysiologic basis of parkinsonian tremor is discussed in terms of the central oscillator and peripheral feedback hypotheses of tremor. Recent studies in monkeys and humans suggest that parkinsonian tremor may result from the activity of a central oscillator, possibly located in the basal ganglia. Peripheral somatosensory input seems to modulate tremor and central nervous system activity related to tremor.

KW - Basal ganglia

KW - Feedback processes

KW - Neuronal oscillators

KW - Parkinson’s disease

KW - Thalamus

KW - Tremor

UR - http://www.scopus.com/inward/record.url?scp=0027159156&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027159156&partnerID=8YFLogxK

U2 - 10.1159/000100595

DO - 10.1159/000100595

M3 - Article

C2 - 8511438

AN - SCOPUS:0027159156

SN - 1011-6125

VL - 60

SP - 94

EP - 103

JO - Stereotactic and Functional Neurosurgery

JF - Stereotactic and Functional Neurosurgery

IS - 1-3

ER -

Role of the thalamus in parkinsonian tremor: Evidence from studies in patients and primate models

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this