Role of routine imaging in lymphoma

Nina Wagner-Johnston, Nancy L. Bartlett

Research output: Contribution to journalArticle

Abstract

Patients with lymphoma commonly undergo routine imaging studies after treatment completion, yet the appropriate interval, duration, and modality of follow-up, and the overall efficacy of various approaches is unclear. Existing guidelines are vague and not evidence-based, and consequently, practice patterns are varied. Most surveillance approaches in lymphoma have focused on early detection of recurrence, with the hope of prolonged survival and potential cure. Concerns regarding the prognostic value of frequent scanning, cost-effectiveness, and long-term risks associated with prolonged radiation exposure have led many to question the role of routine imaging in this setting. Given the multiple lymphoma subtypes and the clinical heterogeneity of these entities, a single approach to follow-up may not be reasonable. Much of the available literature focuses on Hodgkin lymphoma, and may not be generalizable. Retrospective series show that most relapses are detected by signs and symptoms regardless of the imaging schedule. In summary, clinicians are still left with "expert opinion" to guide them. This article examines the available data outlining the role of surveillance imaging in lymphoma.

Original languageEnglish (US)
Pages (from-to)575-585
Number of pages11
JournalJNCCN Journal of the National Comprehensive Cancer Network
Volume9
Issue number5
StatePublished - May 1 2011
Externally publishedYes

Fingerprint

Lymphoma
Recurrence
Evidence-Based Practice
Expert Testimony
Hodgkin Disease
Signs and Symptoms
Cost-Benefit Analysis
Appointments and Schedules
Guidelines
Survival
Therapeutics

Keywords

  • CT
  • Follow-up
  • Hodgkin lymphoma
  • Non-Hodgkin's lymphoma
  • PET/CT
  • Surveillance

ASJC Scopus subject areas

  • Oncology

Cite this

Role of routine imaging in lymphoma. / Wagner-Johnston, Nina; Bartlett, Nancy L.

In: JNCCN Journal of the National Comprehensive Cancer Network, Vol. 9, No. 5, 01.05.2011, p. 575-585.

Research output: Contribution to journalArticle

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