@article{8afef6b2f53743789a8889444d2fac2e,
title = "Role of parental occupation in autism spectrum disorder diagnosis and severity",
abstract = "Some have suggested that parents of children with autism spectrum disorder (ASD) may present with less recognizable autistic-like phenotypic characteristics, leading them to highly systemizing occupations. Using secondary analysis of data from two previous studies of children with ASD, we tested associations between parental occupations and ASD diagnosis and the association of parental occupational characteristics on ASD severity. We found that fathers in healthcare (P < 0.01) and finance (P = 0.03) were more likely to have children with ASD. Additionally, joint effects of parental technical occupations were associated with communication (P < 0.01) and social impairment (P = 0.04). These results support that a {"}broader phenotype{"} and possible assortative mating in adults with autistic-like characteristics might contribute to intergenerational transmission and having offspring with greater ASD severity.",
keywords = "Autism, Diagnosis, Occupation, Parents, Risk, Severity",
author = "Dickerson, {Aisha S.} and Pearson, {Deborah A.} and Loveland, {Katherine A.} and Rahbar, {Mohammad H.} and Filipek, {Pauline A.}",
note = "Funding Information: The original studies for this project were funded by the National Institute of Mental Health (NIMH) Grant: P01 HD035471 , PI: Loveland (Study 1) and the National Institute of Child Health and Human Development (NICHD) Program Project: R01 MH072263 , PI: Pearson (Study 2). This research was completed in partial fulfillment of requirements for the LoneStar Leadership Education in Neurodevelopmental Disabilities (LEND) training program. The LoneStar LEND is a collaboration between The University of Texas Health Science Center at Houston, University of Houston, Texas Woman's University, University of Houston Clear Lake, Baylor College of Medicine and MHMRA of Harris County. The LoneStar LEND is supported by Project # T73MC22236 from the Maternal and Child Health Bureau (Public Health Service Act, Section 399BB (e)(1)(A), as amended by the Combating Autism Act of 2011), Health Resources and Services Administration , Department of Health and Human Services (T37MC22236) . We also acknowledge the support provided by the Biostatistics/ Epidemiology/ Research Design (BERD) component of the Center for Clinical and Translational Sciences (CCTS) for this project. CCTS is mainly funded by the NIH Centers for Translational Science Award (NIH CTSA) grant (UL1 RR024148), awarded to University of Texas Health Science Center at Houston in 2006 by the National Center for Research Resources (NCRR) and its renewal (UL1 TR000371) by the National Center for Advancing Translational Sciences (NCATS).",
year = "2014",
month = sep,
doi = "10.1016/j.rasd.2014.05.007",
language = "English (US)",
volume = "8",
pages = "997--1007",
journal = "Research in Autism Spectrum Disorders",
issn = "1750-9467",
publisher = "Elsevier BV",
number = "9",
}