Role of lipoamide dehydrogenase and metallothionein on 1-methyl-4-phenyl-1, 2,3,6- tetrahydropyridine-induced neurotoxicity

Medicine & Life Sciences

• Dihydrolipoamide Dehydrogenase 100%
• 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine 81%
• 4-phenyl-1,2,3,6-tetrahydropyridine 79%
• Metallothionein 79%
• Ubiquinone 28%
• lipoamide 20%
• ubiquinol 17%
• Enzymes 17%
• 1-Methyl-4-phenylpyridinium 15%
• Flavoproteins 15%
• Caudate Nucleus 12%
• Cadmium 12%
• Putamen 11%
• Sulfhydryl Compounds 11%
• Substantia Nigra 11%
• Copper 10%
• Zinc 10%
• Metals 9%
• Parkinson Disease 8%
• Molecular Weight 8%
• Poisons 7%
• Calcium 7%

Chemical Compounds

• Lipoamide 98%
• Neurotoxicity 80%
• Dose 20%
• 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 14%
• Ubiquinol 13%
• Neurotoxic 11%
• Ubiquinone 11%
• Flavoprotein 11%
• Thiol 7%
• Enzyme Activity 7%
• Calcium(0) 7%
• Toxic 6%
• Metal 4%