Role of Immune Cells in Acute Kidney Injury and Repair

Sul A. Lee, Sanjeev Noel, Mohanraj Sadasivam, Abdel R.A. Hamad, Hamid Rabb

Research output: Contribution to journalReview articlepeer-review

Abstract

Acute kidney injury (AKI) is a significant problem in both native and transplant kidneys. There have been significant advances in understanding the role of immune cells in the early injury and repair from AKI. In this brief review, we aim to update information on the pathophysiologic impact of various immune cells in AKI, with special emphasis on repair. An improved understanding of the AKI immunopathology will lead to new therapies that prevent AKI, accelerate repair, and prevent the progression of AKI to chronic kidney disease.

Original languageEnglish (US)
Pages (from-to)282-286
Number of pages5
JournalNephron
Volume137
Issue number4
DOIs
StatePublished - Nov 1 2017

ASJC Scopus subject areas

  • Physiology
  • Nephrology
  • Physiology (medical)
  • Urology

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