Role of Fractional-Flow Reserve in Guiding Percutaneous Revascularization in Stable Coronary Artery Disease

Nikolaos Kakouros, Jeffrey J. Rade

Research output: Contribution to journalArticle

Abstract

Optimal medical therapy unarguably forms the cornerstone of management for patients with stable coronary artery disease. There is, however, a significant body of evidence suggesting that reduction of ischemia can be achieved more effectively with revascularization than medical therapy and can confer significant symptomatic and prognostic advantages. Nonetheless, owing to limitations of coronary angiography and conventional non-invasive functional testing for myocardial ischemia, targeting of hemodynamically significant coronary stenoses for revascularization is often difficult. We discuss the role of invasive fractional-flow reserve evaluation in guiding percutaneous revascularization procedures for patients with stable coronary artery disease and its potential impact on outcomes for these patients.

Original languageEnglish (US)
Article number52
JournalCurrent Atherosclerosis Reports
Volume17
Issue number9
DOIs
StatePublished - Sep 27 2015
Externally publishedYes

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Coronary Artery Disease
Coronary Stenosis
Coronary Angiography
Myocardial Ischemia
Ischemia
Therapeutics

Keywords

  • Clinical trials
  • Coronary artery disease
  • Coronary physiology
  • Fractional flow reserve

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Role of Fractional-Flow Reserve in Guiding Percutaneous Revascularization in Stable Coronary Artery Disease. / Kakouros, Nikolaos; Rade, Jeffrey J.

In: Current Atherosclerosis Reports, Vol. 17, No. 9, 52, 27.09.2015.

Research output: Contribution to journalArticle

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