Considerable serological evidence for the association of the Eaton agent and viral pneumonia with or without cold agglutinins or Streptococcus MG antibody rises was obtained by use of the indirect fluorescent antibody test. In two instances serological rises to the agent were substantiated by isolation of a strain of the Eaton agent from the sputum of the patient. Antigenic variation and non-specific reactions could nose be demonstrated. Prevalence of fluorescent antibody to the Eaton agent in a general population group suggests that it is a wide-spread and common infection which may occur in all age-groups. Infection with the agent may occur in any month of the year.
ASJC Scopus subject areas