Role of dental hardware in oral cavity squamous cell carcinoma in the low-risk nonsmoker nondrinker population

Jessica A. Yesensky, Rifat Hasina, Kristen E. Wroblewski, Joseph Bellairs, Zhen Gooi, Vassiliki Saloura, Nicole A. Cipriani, Everett E. Vokes, Louis G. Portugal, Tanguy Lim Seiwert, Elizabeth D. Blair, Nishant Agrawal

Research output: Contribution to journalArticle

Abstract

Background: Oral cavity squamous cell carcinoma (SCC) arising in nonsmokers and nondrinkers remains poorly characterized. We hypothesized that these patients had prior exposure to metallic dental hardware. Methods: We utilized a questionnaire querying the lifetime oral health status of 54 patients. Demographics and extensive oral health history were collected. Results: The majority of patients (74%) had prior exposure to metallic dental hardware. The younger population with almost exclusively oral tongue cancer had a high prevalence of metallic orthodontic braces (40%) within 15 years before diagnosis. In the 51+ year age group, 82% had crowns, dental implants, and/or dentures with metallic elements. Conclusion: Exposure to metallic dental hardware has increased in the past few decades given the rise of orthodontic braces and older adults retaining more teeth. Although this study does not prove a causal relationship between oral cavity SCC and dental hardware, this is a step toward identifying and investigating their role.

Original languageEnglish (US)
Pages (from-to)784-792
Number of pages9
JournalHead and Neck
Volume40
Issue number4
DOIs
StatePublished - Apr 1 2018
Externally publishedYes

Fingerprint

Mouth
Squamous Cell Carcinoma
Tooth
Orthodontic Brackets
Population
Oral Health
Tongue Neoplasms
Dental Implants
Dentures
Mouth Neoplasms
Crowns
Health Status
Age Groups
Demography
Interviews

Keywords

  • dental care
  • head and neck squamous cell carcinoma
  • oral cavity squamous cell carcinoma (OCSCC)
  • oral health
  • risk factors

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Yesensky, J. A., Hasina, R., Wroblewski, K. E., Bellairs, J., Gooi, Z., Saloura, V., ... Agrawal, N. (2018). Role of dental hardware in oral cavity squamous cell carcinoma in the low-risk nonsmoker nondrinker population. Head and Neck, 40(4), 784-792. https://doi.org/10.1002/hed.25059

Role of dental hardware in oral cavity squamous cell carcinoma in the low-risk nonsmoker nondrinker population. / Yesensky, Jessica A.; Hasina, Rifat; Wroblewski, Kristen E.; Bellairs, Joseph; Gooi, Zhen; Saloura, Vassiliki; Cipriani, Nicole A.; Vokes, Everett E.; Portugal, Louis G.; Lim Seiwert, Tanguy; Blair, Elizabeth D.; Agrawal, Nishant.

In: Head and Neck, Vol. 40, No. 4, 01.04.2018, p. 784-792.

Research output: Contribution to journalArticle

Yesensky, JA, Hasina, R, Wroblewski, KE, Bellairs, J, Gooi, Z, Saloura, V, Cipriani, NA, Vokes, EE, Portugal, LG, Lim Seiwert, T, Blair, ED & Agrawal, N 2018, 'Role of dental hardware in oral cavity squamous cell carcinoma in the low-risk nonsmoker nondrinker population', Head and Neck, vol. 40, no. 4, pp. 784-792. https://doi.org/10.1002/hed.25059
Yesensky JA, Hasina R, Wroblewski KE, Bellairs J, Gooi Z, Saloura V et al. Role of dental hardware in oral cavity squamous cell carcinoma in the low-risk nonsmoker nondrinker population. Head and Neck. 2018 Apr 1;40(4):784-792. https://doi.org/10.1002/hed.25059
Yesensky, Jessica A. ; Hasina, Rifat ; Wroblewski, Kristen E. ; Bellairs, Joseph ; Gooi, Zhen ; Saloura, Vassiliki ; Cipriani, Nicole A. ; Vokes, Everett E. ; Portugal, Louis G. ; Lim Seiwert, Tanguy ; Blair, Elizabeth D. ; Agrawal, Nishant. / Role of dental hardware in oral cavity squamous cell carcinoma in the low-risk nonsmoker nondrinker population. In: Head and Neck. 2018 ; Vol. 40, No. 4. pp. 784-792.
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