The pathogenesis of Sindbis virus infection was studied in congenic mice with normal levels of the fifth component of complement (C5) and in mice deficient in C5. Mice deficient in C5 had a higher mortality rate than mice with normal levels of C5 as well as impaired clearance of virus from their brains and feet.
|Original language||English (US)|
|Number of pages||3|
|Journal||Infection and immunity|
|State||Published - Dec 1 1980|
ASJC Scopus subject areas
- Infectious Diseases