Role of Academic Drug Discovery in the Quest for New CNS Therapeutics

Brian H. Yokley; Matthew Hartman; Barbara S. Slusher

doi:10.1021/acschemneuro.7b00040

Role of Academic Drug Discovery in the Quest for New CNS Therapeutics

Brian H. Yokley, Matthew Hartman, Barbara S. Slusher

School of Medicine

Research output: Contribution to journal › Review article › peer-review

11 Scopus citations

Abstract

There was a greater than 50% decline in central nervous system (CNS) drug discovery and development programs by major pharmaceutical companies from 2009 to 2014. This decline was paralleled by a rise in the number of university led drug discovery centers, many in the CNS area, and a growth in the number of public-private drug discovery partnerships. Diverse operating models have emerged as the academic drug discovery centers adapt to this changing ecosystem.

Original language	English (US)
Pages (from-to)	429-431
Number of pages	3
Journal	ACS Chemical Neuroscience
Volume	8
Issue number	3
DOIs	https://doi.org/10.1021/acschemneuro.7b00040
State	Published - Mar 15 2017

Keywords

Academic drug discovery
public-private partnerships

ASJC Scopus subject areas

Biochemistry
Physiology
Cognitive Neuroscience
Cell Biology

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10.1021/acschemneuro.7b00040

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abstract = "There was a greater than 50% decline in central nervous system (CNS) drug discovery and development programs by major pharmaceutical companies from 2009 to 2014. This decline was paralleled by a rise in the number of university led drug discovery centers, many in the CNS area, and a growth in the number of public-private drug discovery partnerships. Diverse operating models have emerged as the academic drug discovery centers adapt to this changing ecosystem.",

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AB - There was a greater than 50% decline in central nervous system (CNS) drug discovery and development programs by major pharmaceutical companies from 2009 to 2014. This decline was paralleled by a rise in the number of university led drug discovery centers, many in the CNS area, and a growth in the number of public-private drug discovery partnerships. Diverse operating models have emerged as the academic drug discovery centers adapt to this changing ecosystem.

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Role of Academic Drug Discovery in the Quest for New CNS Therapeutics

Abstract

Keywords

ASJC Scopus subject areas

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