Robust treatment planning in whole pelvis pencil beam scanning proton therapy for prostate cancer: Whole Pelvis Proton Therapy Planning

Anish A. Butala, W. Scott Ingram, Shannon E. O'Reilly, Brett Hartl, Ali Kassaee, Curtiland Deville, Neha Vapiwala

Research output: Contribution to journalArticle

Abstract

Whole-pelvis pencil beam scanning (PBS) proton therapy is utilized in both the intact and post-operative settings in patients with prostate cancer. As whole pelvis prostate radiotherapy has traditionally been delivered with standard photon beams, limited evidence and technical descriptions have been reported regarding the use of proton therapy. Here we present two robust three-field treatment planning approaches utilized to maximize target coverage in the presence of anatomic and delivery uncertainties. Both techniques, conventional optimization (CO) and robust optimization (RO), create treatment plans with acceptable target coverage and sparing of organs at risk (OAR). While the RO method is less time intensive and may theoretically allow for superior OAR sparing and improved robustness, the CO method can be implemented by institutions who do not have RO capabilities.

Original languageEnglish (US)
JournalMedical Dosimetry
DOIs
StateAccepted/In press - 2020

Keywords

  • Conventional optimization
  • Pencil beam scanning
  • Proton therapy
  • Robust optimization
  • Whole pelvis

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Oncology
  • Radiology Nuclear Medicine and imaging

Fingerprint Dive into the research topics of 'Robust treatment planning in whole pelvis pencil beam scanning proton therapy for prostate cancer: Whole Pelvis Proton Therapy Planning'. Together they form a unique fingerprint.

  • Cite this