Robust spectral-domain optical coherence tomography speckle model and its cross-correlation coefficient analysis

Xuan Liu, Jessica C. Ramella-Roman, Yong Huang, Yuan Guo, Jin U. Kang

Research output: Contribution to journalArticlepeer-review

Abstract

In this study, we propose a generic speckle simulation for optical coherence tomography (OCT) signal, by convolving the point-spread function (PSF) of the OCT system with the numerically synthesized random sample field. We validate our model and use the simulation method to study the statistical properties of cross-correlation coefficients between A-scans, which have been recently applied in transverse motion analysis by our group. The results of simulation show that oversampling is essential for accurate motion tracking; exponential decay of OCT signal leads to an underestimate of motion that can be corrected; lateral heterogeneity of sample leads to an overestimate of motion for a few pixels corresponding to the structural boundary.

Original languageEnglish (US)
Pages (from-to)51-59
Number of pages9
JournalJournal of the Optical Society of America A: Optics and Image Science, and Vision
Volume30
Issue number1
DOIs
StatePublished - 2013
Externally publishedYes

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Computer Vision and Pattern Recognition
  • Medicine(all)

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