Robust high-resolution fine OCT needle for side-viewing interstitial tissue imaging

Yicong Wu; Jiefeng Xi; Li Huo; Jason Padvorac; Eun Ji Shin; Samuel A. Giday; Anne Marie Lennon; Marcia Irene F. Canto; Joo Ha Hwang; Xingde Li

doi:10.1109/JSTQE.2009.2035362

Robust high-resolution fine OCT needle for side-viewing interstitial tissue imaging

Yicong Wu, Jiefeng Xi, Li Huo, Jason Padvorac, Eun Ji Shin, Samuel A. Giday, Anne Marie Lennon, Marcia Irene F. Canto, Joo Ha Hwang, Xingde Li

School of Medicine

Research output: Contribution to journal › Article › peer-review

41 Scopus citations

Abstract

Fine optical coherence tomography (OCT) imaging needles that can be integrated with a standard biopsy needle have been developed with a new optics design to improve the optical quality and mechanical robustness, where a fiber-optic lens (that is spliced to a single-mode fiber) and a microreflector are encased within a microglass tube. The design also minimizes the cylindrical lens effect induced by the glass tube and eases the needle assembly process. Real-time cross-sectional OCT imaging of various tissue samples were performed ex vivo using the miniature-imaging needle along with a 1300-nm swept-source OCT system. The preliminary results demonstrate the improved mechanical and optical performance and suggest the potential of the fine OCT needle for minimally invasive interstitial imaging and image-guided biopsy.

Original language	English (US)
Article number	5353608
Pages (from-to)	863-869
Number of pages	7
Journal	IEEE Journal on Selected Topics in Quantum Electronics
Volume	16
Issue number	4
DOIs	https://doi.org/10.1109/JSTQE.2009.2035362
State	Published - Jul 2010

Keywords

Astigmatism
OCT needle
biopsy needle
interstitial imaging
optical coherence tomography (OCT)

ASJC Scopus subject areas

Atomic and Molecular Physics, and Optics
Electrical and Electronic Engineering

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10.1109/JSTQE.2009.2035362

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title = "Robust high-resolution fine OCT needle for side-viewing interstitial tissue imaging",

abstract = "Fine optical coherence tomography (OCT) imaging needles that can be integrated with a standard biopsy needle have been developed with a new optics design to improve the optical quality and mechanical robustness, where a fiber-optic lens (that is spliced to a single-mode fiber) and a microreflector are encased within a microglass tube. The design also minimizes the cylindrical lens effect induced by the glass tube and eases the needle assembly process. Real-time cross-sectional OCT imaging of various tissue samples were performed ex vivo using the miniature-imaging needle along with a 1300-nm swept-source OCT system. The preliminary results demonstrate the improved mechanical and optical performance and suggest the potential of the fine OCT needle for minimally invasive interstitial imaging and image-guided biopsy.",

keywords = "Astigmatism, OCT needle, biopsy needle, interstitial imaging, optical coherence tomography (OCT)",

author = "Yicong Wu and Jiefeng Xi and Li Huo and Jason Padvorac and Shin, {Eun Ji} and Giday, {Samuel A.} and Lennon, {Anne Marie} and Canto, {Marcia Irene F.} and Hwang, {Joo Ha} and Xingde Li",

note = "Funding Information: Manuscript received September 15, 2009; revised October 19, 2009; accepted October 19, 2009 . Date of publication December 15, 2009 ; date of current version August 6, 2010. This work was supported in part by the National Institutes of Health under Grant R21 CA116442 and Grant R01 CA120480, the National Science Foundation Career Award (XDL), and by the Alexander H. Steinkoler Pancreatic Cancer Foundation. Copyright: Copyright 2010 Elsevier B.V., All rights reserved.",

year = "2010",

month = jul,

doi = "10.1109/JSTQE.2009.2035362",

language = "English (US)",

volume = "16",

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AU - Xi, Jiefeng

AU - Huo, Li

AU - Padvorac, Jason

AU - Shin, Eun Ji

AU - Giday, Samuel A.

AU - Lennon, Anne Marie

AU - Canto, Marcia Irene F.

AU - Hwang, Joo Ha

AU - Li, Xingde

N1 - Funding Information: Manuscript received September 15, 2009; revised October 19, 2009; accepted October 19, 2009 . Date of publication December 15, 2009 ; date of current version August 6, 2010. This work was supported in part by the National Institutes of Health under Grant R21 CA116442 and Grant R01 CA120480, the National Science Foundation Career Award (XDL), and by the Alexander H. Steinkoler Pancreatic Cancer Foundation. Copyright: Copyright 2010 Elsevier B.V., All rights reserved.

PY - 2010/7

Y1 - 2010/7

N2 - Fine optical coherence tomography (OCT) imaging needles that can be integrated with a standard biopsy needle have been developed with a new optics design to improve the optical quality and mechanical robustness, where a fiber-optic lens (that is spliced to a single-mode fiber) and a microreflector are encased within a microglass tube. The design also minimizes the cylindrical lens effect induced by the glass tube and eases the needle assembly process. Real-time cross-sectional OCT imaging of various tissue samples were performed ex vivo using the miniature-imaging needle along with a 1300-nm swept-source OCT system. The preliminary results demonstrate the improved mechanical and optical performance and suggest the potential of the fine OCT needle for minimally invasive interstitial imaging and image-guided biopsy.

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Robust high-resolution fine OCT needle for side-viewing interstitial tissue imaging

Abstract

Keywords

ASJC Scopus subject areas

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