TY - GEN
T1 - Robust computation of mutual information using spatially adaptive meshes
AU - Sundar, Hari
AU - Shen, Dinggang
AU - Biros, George
AU - Xu, Chenyang
AU - Davatzikos, Christos
PY - 2007
Y1 - 2007
N2 - We present a new method for the fast and robust computation of information theoretic similarity measures for alignment of multi-modality medical images. The proposed method defines a non-uniform, adaptive sampling scheme for estimating the entropies of the images, which is less vulnerable to local maxima as compared to uniform and random sampling. The sampling is defined using an octree partition of the template image, and is preferable over other proposed methods of non-uniform sampling since it respects the underlying data distribution. It also extends naturally to a multi-resolution registration approach, which is commonly employed in the alignment of medical images. The effectiveness of the proposed method is demonstrated using both simulated MR images obtained from the BrainWeb database and clinical CT and SPECT images.
AB - We present a new method for the fast and robust computation of information theoretic similarity measures for alignment of multi-modality medical images. The proposed method defines a non-uniform, adaptive sampling scheme for estimating the entropies of the images, which is less vulnerable to local maxima as compared to uniform and random sampling. The sampling is defined using an octree partition of the template image, and is preferable over other proposed methods of non-uniform sampling since it respects the underlying data distribution. It also extends naturally to a multi-resolution registration approach, which is commonly employed in the alignment of medical images. The effectiveness of the proposed method is demonstrated using both simulated MR images obtained from the BrainWeb database and clinical CT and SPECT images.
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M3 - Conference contribution
SN - 9783540757566
VL - 4791 LNCS
T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
SP - 950
EP - 958
BT - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
T2 - 10th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2007
Y2 - 29 October 2007 through 2 November 2007
ER -