Rnakinetics: A web server that models secondary structure kinetics of an elongating RNA

Ludmila V. Danilova, Dmitri D. Pervouchine, Alexander V. Favorov, Andrei A. Mironov

Research output: Contribution to journalArticlepeer-review

Abstract

The RNAKinetics server (http://www.ig-msk.ru/RNA/kinetics) is a web interface for the newly developed RNAKinetics software. The software models the dynamics of RNA secondary structure by the means of kinetic analysis of folding transitions of a growing RNA molecule. The result of the modeling is a kinetic ensemble, i.e. a collection of RNA structures that are endowed with probabilities, which depend on time. This approach gives comprehensive probabilistic description of RNA folding pathways, revealing important kinetic details that are not captured by the traditional structure prediction methods. The access to the RNAKinetics server is free.

Original languageEnglish (US)
Pages (from-to)589-596
Number of pages8
JournalJournal of Bioinformatics and Computational Biology
Volume4
Issue number2
DOIs
StatePublished - Apr 2006
Externally publishedYes

Keywords

  • Dynamics
  • Kinetics
  • RNA folding
  • RNA secondary structure

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Computer Science Applications

Fingerprint Dive into the research topics of 'Rnakinetics: A web server that models secondary structure kinetics of an elongating RNA'. Together they form a unique fingerprint.

Cite this