Abstract
Most children with acute immune thrombocytopenic purpura (ITP) respond to first-line therapies including intravenous immunoglobulin, corticosteroids, and Rho(D) immune globulin. However, there is no clear consensus regarding second-line therapies for the treatment of ITP, not responding to first-line therapies in the acute setting. Adapting from the chronic ITP literature, 3 patients with acute refractory ITP were treated with intravenous rituximab and showed immediate and sustained remission. Combined therapy that includes rituximab may be an effective regimen for acute refractory ITP.
Original language | English (US) |
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Pages (from-to) | e149-e151 |
Journal | Journal of Pediatric Hematology/Oncology |
Volume | 36 |
Issue number | 3 |
DOIs | |
State | Published - Apr 2014 |
Externally published | Yes |
Keywords
- Acute immune thrombocytopenic purpura
- children
- rituximab
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Hematology
- Oncology