Risks of allergy vial contamination: Comparison of mixing in-office versus under ventilation hood

P. Chase Lay, Richard Bass, Larry F. Hughes, Sandra Y. Lin

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: Compare the risk of bacterial contamination of allergy immunotherapy vials prepared in-office versus those mixed under a ventilation hood. Study Design: Prospective single-blinded study. Setting: Tertiary otolaryngology outpatient clinic. Results: Five hundred thirty-seven vials were prepared and cultured for aerobes and anaerobes over an 11-month period. Three hundred twenty vials were arbitrarily assigned to in-office preparation and 217 to under-hood preparation. A total of two positive cultures occurred in vials prepared in-office and one from under-hood preparation. Follow-up cultures of these three vials were all negative. No patients receiving injections had signs or symptoms of skin or systemic infections from the injections. Conclusion: Our results suggest that the risk of bacterial contamination in immunotherapy vials in both groups is rare.

Original languageEnglish (US)
Pages (from-to)364-366
Number of pages3
JournalOtolaryngology - Head and Neck Surgery
Volume139
Issue number3
DOIs
StatePublished - Sep 1 2008

ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology

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