The role that diet and lifestyle factors play in prostate carcinogenesis remains controversial. Nonetheless, several lines of evidence suggest that lifestyle could have a large influence on prostate cancer occurrence or progression. First, large interpopulation differences in rates of prostate cancer incidence or mortality are observed, which probably cannot be explained solely by genetic differences among these populations.1 Studies have demonstrated strong correlations between per capita measures of various foods or nutrients and prostate cancer mortality.2,3 Although the specificity of these associations may be questioned, they do indicate that some dietary component or pattern influences prostate cancer. Second, rates of prostate cancer have been shown to increase with changing lifestyle patterns within populations, and migrating populations tend to take on the prostate cancer experience of the new country.4 Third, although the results have not been entirely consistent, numerous epidemiologic studies have correlated specific dietary factors with risk of prostate cancer. Factors that have been shown to increase risk include higher intake of red and processed meat and dairy products, and those that decrease risk include higher intake of tomato products, which contain the carotenoid lycopene, and selenium, and supplemental intake of vitamin E.
|Original language||English (US)|
|Title of host publication||Prostate Cancer|
|Subtitle of host publication||Principles and Practice|
|Number of pages||9|
|State||Published - Jan 1 2005|
ASJC Scopus subject areas