TY - JOUR
T1 - Risk factors for primary middle east respiratory syndrome coronavirus illness in humans, Saudi Arabia, 2014
AU - Alraddadi, Basem M.
AU - Watson, John T.
AU - Almarashi, Abdulatif
AU - Abedi, Glen R.
AU - Turkistani, Amal
AU - Sadran, Musallam
AU - Housa, Abeer
AU - Almazroa, Mohammad A.
AU - Alraihan, Naif
AU - Banjar, Ayman
AU - Albalawi, Eman
AU - Alhindi, Hanan
AU - Choudhry, Abdul Jamil
AU - Meiman, Jonathan G.
AU - Paczkowski, Magdalena
AU - Curns, Aaron
AU - Mounts, Anthony
AU - Feikin, Daniel R.
AU - Marano, Nina
AU - Swerdlow, David L.
AU - Gerber, Susan I.
AU - Hajjeh, Rana
AU - Madani, Tariq A.
N1 - Publisher Copyright:
© 2016, Centers for Disease Control and Prevention (CDC). All rights reseved.
PY - 2016/1
Y1 - 2016/1
N2 - Risk factors for primary Middle East respiratory syndrome coronavirus (MERS-CoV) illness in humans are incompletely understood. We identified all primary MERS-CoV cases reported in Saudi Arabia during March–November 2014 by excluding those with history of exposure to other cases of MERS-CoV or acute respiratory illness of unknown cause or exposure to healthcare settings within 14 days before illness onset. Using a case–control design, we assessed differences in underlying medical conditions and environmental exposures among primary case-patients and 2–4 controls matched by age, sex, and neighborhood. Using multivariable analysis, we found that direct exposure to dromedary camels during the 2 weeks before illness onset, as well as diabetes mellitus, heart disease, and smoking, were each independently associated with MERS-CoV illness. Further investigation is needed to better understand animal-to-human transmission of MERS-CoV.
AB - Risk factors for primary Middle East respiratory syndrome coronavirus (MERS-CoV) illness in humans are incompletely understood. We identified all primary MERS-CoV cases reported in Saudi Arabia during March–November 2014 by excluding those with history of exposure to other cases of MERS-CoV or acute respiratory illness of unknown cause or exposure to healthcare settings within 14 days before illness onset. Using a case–control design, we assessed differences in underlying medical conditions and environmental exposures among primary case-patients and 2–4 controls matched by age, sex, and neighborhood. Using multivariable analysis, we found that direct exposure to dromedary camels during the 2 weeks before illness onset, as well as diabetes mellitus, heart disease, and smoking, were each independently associated with MERS-CoV illness. Further investigation is needed to better understand animal-to-human transmission of MERS-CoV.
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U2 - 10.3201/eid2201.151340
DO - 10.3201/eid2201.151340
M3 - Article
C2 - 26692185
AN - SCOPUS:84950291086
SN - 1080-6040
VL - 22
SP - 49
EP - 55
JO - Emerging infectious diseases
JF - Emerging infectious diseases
IS - 1
ER -