Risk factors for persistent diarrhoea

N. S. Shahid, David Allen Sack, M. Rahman, A. N. Alam, N. Rahman

Research output: Contribution to journalArticle

Abstract

With a systematically sampled population of children aged under 5 attending this centre for diarrhoeal disease research during 1983-5 a retrospective analysis of persistent diarrhoea (defined as >14 days' duration) was performed to identify the possible risk factors for this syndrome. Of the 4155 children included in the analysis, 410 (10%) gave a history of persistent diarrhoea. A comparison with children with acute diarrhoea matched for age showed that 11 factors were correlated with persistent diarrhoea, and strongly associated factors were stools with blood or mucus, or both, lower respiratory tract infection, malnutrition, vitamin A deficiency, and antibiotic use before presentation. The peak age was 2 years, and there was no sex difference. Deaths occurred more often in the group with persistent diarrhoea. Although Shigella spp, Campylobacter jejuni, and Giardia lamblia were frequently identified, their rates of isolation were not significantly higher among patients with persistent diarrhoea. No seasonal variation was observed in the rates of persistent diarrhoea. Although the introduction of family food to the diet was associated with higher rates, this factor was difficult to separate from the age dependent risks.

Original languageEnglish (US)
Pages (from-to)1036-1038
Number of pages3
JournalBMJ (Online)
Volume297
Issue number6655
StatePublished - 1988

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Diarrhea
Vitamin A Deficiency
Giardia lamblia
Campylobacter jejuni
Shigella
Mucus
Malnutrition
Sex Characteristics
Respiratory Tract Infections
Anti-Bacterial Agents
Diet
Food
Research
Population

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Shahid, N. S., Sack, D. A., Rahman, M., Alam, A. N., & Rahman, N. (1988). Risk factors for persistent diarrhoea. BMJ (Online), 297(6655), 1036-1038.

Risk factors for persistent diarrhoea. / Shahid, N. S.; Sack, David Allen; Rahman, M.; Alam, A. N.; Rahman, N.

In: BMJ (Online), Vol. 297, No. 6655, 1988, p. 1036-1038.

Research output: Contribution to journalArticle

Shahid, NS, Sack, DA, Rahman, M, Alam, AN & Rahman, N 1988, 'Risk factors for persistent diarrhoea', BMJ (Online), vol. 297, no. 6655, pp. 1036-1038.
Shahid NS, Sack DA, Rahman M, Alam AN, Rahman N. Risk factors for persistent diarrhoea. BMJ (Online). 1988;297(6655):1036-1038.
Shahid, N. S. ; Sack, David Allen ; Rahman, M. ; Alam, A. N. ; Rahman, N. / Risk factors for persistent diarrhoea. In: BMJ (Online). 1988 ; Vol. 297, No. 6655. pp. 1036-1038.
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