Risk factors for emergence of resistance to broad-spectrum cephalosporins among Enterobacter spp.

K. S. Kaye, S. Cosgrove, A. Harris, G. M. Eliopoulos, Y. Carmeli

Research output: Contribution to journalArticlepeer-review

Abstract

Among 477 patients with susceptible Enterobacter spp., 49 subsequently harbored third-generation cephalosporin-resistant Enterobacter spp. Broad-spectrum cephalosporins were independent risk factors for resistance (relative risk [OR] = 2.3, P = 0.01); quinolone therapy was protective (OR = 0.4, P = 0.03). There were trends toward decreased risk for resistance among patients receiving broad-spectrum cephalosporins and either aminoglycosides or imipenem. Of the patients receiving broad-spectrum cephalosporins, 19% developed resistance.

Original languageEnglish (US)
Pages (from-to)2628-2630
Number of pages3
JournalAntimicrobial agents and chemotherapy
Volume45
Issue number9
DOIs
StatePublished - 2001
Externally publishedYes

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

Fingerprint Dive into the research topics of 'Risk factors for emergence of resistance to broad-spectrum cephalosporins among Enterobacter spp.'. Together they form a unique fingerprint.

Cite this