Risk factors for developing active tuberculosis after the treatment of latent tuberculosis in adults infected with human immunodeficiency virus

Kojo Amoakwa; Neil A. Martinson; Lawrence H. Moulton; Grace L. Barnes; Reginah Msandiwa; Richard E. Chaisson

doi:10.1093/ofid/ofu120

Risk factors for developing active tuberculosis after the treatment of latent tuberculosis in adults infected with human immunodeficiency virus

Kojo Amoakwa, Neil A. Martinson, Lawrence H. Moulton, Grace L. Barnes, Reginah Msandiwa, Richard E. Chaisson

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Tuberculosis is the leading cause of death among adults infected with human immunodeficiency virus (HIV), and rates of tuberculosis remain high even after preventive therapy. Among 908 HIV-infected adults in a trial of preventive treatment, we found self-reported alcohol consumption, low baseline CD4 count, high baseline viral load, and tuberculin skin test size >15 mmas independent risk factors for incident tuberculosis.

Original language	English (US)
Journal	Open Forum Infectious Diseases
Volume	2
Issue number	1
DOIs	https://doi.org/10.1093/ofid/ofu120
State	Published - Jan 1 2015

Keywords

Baseline
HIV-infected adults
Latent tuberculosis
Preventive therapy
Risk

ASJC Scopus subject areas

Oncology
Clinical Neurology

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10.1093/ofid/ofu120

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title = "Risk factors for developing active tuberculosis after the treatment of latent tuberculosis in adults infected with human immunodeficiency virus",

abstract = "Tuberculosis is the leading cause of death among adults infected with human immunodeficiency virus (HIV), and rates of tuberculosis remain high even after preventive therapy. Among 908 HIV-infected adults in a trial of preventive treatment, we found self-reported alcohol consumption, low baseline CD4 count, high baseline viral load, and tuberculin skin test size >15 mmas independent risk factors for incident tuberculosis.",

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AU - Barnes, Grace L.

AU - Msandiwa, Reginah

AU - Chaisson, Richard E.

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AB - Tuberculosis is the leading cause of death among adults infected with human immunodeficiency virus (HIV), and rates of tuberculosis remain high even after preventive therapy. Among 908 HIV-infected adults in a trial of preventive treatment, we found self-reported alcohol consumption, low baseline CD4 count, high baseline viral load, and tuberculin skin test size >15 mmas independent risk factors for incident tuberculosis.

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KW - Preventive therapy

KW - Risk

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Risk factors for developing active tuberculosis after the treatment of latent tuberculosis in adults infected with human immunodeficiency virus

Abstract

Keywords

ASJC Scopus subject areas

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