Risk factors for developing active tuberculosis after the treatment of latent tuberculosis in adults infected with human immunodeficiency virus

Kojo Amoakwa, Neil A. Martinson, Lawrence H. Moulton, Grace L. Barnes, Reginah Msandiwa, Richard E. Chaisson

Research output: Contribution to journalArticlepeer-review

Abstract

Tuberculosis is the leading cause of death among adults infected with human immunodeficiency virus (HIV), and rates of tuberculosis remain high even after preventive therapy. Among 908 HIV-infected adults in a trial of preventive treatment, we found self-reported alcohol consumption, low baseline CD4 count, high baseline viral load, and tuberculin skin test size >15 mmas independent risk factors for incident tuberculosis.

Original languageEnglish (US)
JournalOpen Forum Infectious Diseases
Volume2
Issue number1
DOIs
StatePublished - Jan 1 2015

Keywords

  • Baseline
  • HIV-infected adults
  • Latent tuberculosis
  • Preventive therapy
  • Risk

ASJC Scopus subject areas

  • Oncology
  • Clinical Neurology

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