Risk Factors for Complications Requiring Interventional Radiological Treatment After Hepatectomy

Andrew R. Kolarich, Alex J. Solomon, Matthew J. Weiss, Benjamin Philosophe, Clifford R. Weiss, Kelvin Hong

Research output: Contribution to journalArticle

Abstract

Purpose: To identify perioperative factors that are significantly associated with complications requiring interventional radiology (IR) treatment after hepatectomy. Methods: We retrospectively reviewed data from 11,243 patients in the USA who underwent hepatectomy from 2014 to 2016 using the National Surgical Quality Improvement Program database. Data on the following IR procedures were extracted: abscess drain placement, endovascular treatment for bleeding, and postoperative percutaneous biliary drain (PBD) placement up to 30 days postoperatively. Patients’ clinical and intraoperative factors were examined. Population, univariate, and multivariable analyses were performed. P < 0.05 was considered significant. Results: A total of 704 patients (6%) required IR treatment postoperatively, and 10,539 patients (94%) did not. On multivariable analysis, biliary reconstruction was a significant predictor of postoperative abscess drain placement (hazard ratio (HR), 3.5; 95% confidence interval (CI) 1.8, 6.5; P <.001), endovascular treatment for bleeding (HR, 3.3; 95% CI 1.4, 7.8 P =.006), and postoperative PBD placement (HR, 2.9; 95% CI 1.9, 4.2; P <.001). Compared with hepatectomy without biliary reconstruction, hepatectomy with biliary reconstruction was associated with significantly higher rates of complications treated with IR procedures (26% vs. 4.9%) and death within 30 days (6.0% vs. 1.2%) (both, P <.001). Conclusion: Biliary reconstruction is a strong predictor of the need for postoperative IR treatment after hepatectomy. One in four patients who underwent biliary reconstruction required IR treatment of a complication during the first 30 days after hepatectomy.

Original languageEnglish (US)
JournalJournal of Gastrointestinal Surgery
DOIs
StateAccepted/In press - 2020

Keywords

  • Biliary drain
  • Biliary reconstruction
  • Embolization
  • Hepatectomy
  • National Surgical Quality Improvement Program

ASJC Scopus subject areas

  • Surgery
  • Gastroenterology

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