Abstract
Vasospasm is a major cause of morbidity and mortality following aneurysmal subarachnoid hemorrhage. This article reviews the risk factors for vasospasm; the various methods for diagnosing vasospasm including the conventional 4-vessel angiography, computed tomographic angiography, and computed tomographic perfusion; the methods to detect vasospasm before clinical onset (including transcranial Doppler ultrasonography); and the recent emergence of multimodality monitoring. A discussion of medical treatment options in the setting of vasospasm is also included; the prophylactic use of " neuroprotectants" such as nimodipine, statins, and magnesium and the role of hemodynamic augmentation in vasospasm amelioration, including the use of inotropic support in addition to traditional triple-H therapy, are discussed.
Original language | English (US) |
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Pages (from-to) | 353-364 |
Number of pages | 12 |
Journal | Neurosurgery clinics of North America |
Volume | 21 |
Issue number | 2 |
DOIs | |
State | Published - Apr 2010 |
Externally published | Yes |
Keywords
- Aneurysmal subarachnoid hemorrhage
- Cerebral blood flow
- Triple-H therapy
- Vasospasm
ASJC Scopus subject areas
- Surgery
- Clinical Neurology