Risk Factors and Medical Management of Vasospasm After Subarachnoid Hemorrhage

Christos Lazaridis, Neeraj Naval

Research output: Contribution to journalArticle

Abstract

Vasospasm is a major cause of morbidity and mortality following aneurysmal subarachnoid hemorrhage. This article reviews the risk factors for vasospasm; the various methods for diagnosing vasospasm including the conventional 4-vessel angiography, computed tomographic angiography, and computed tomographic perfusion; the methods to detect vasospasm before clinical onset (including transcranial Doppler ultrasonography); and the recent emergence of multimodality monitoring. A discussion of medical treatment options in the setting of vasospasm is also included; the prophylactic use of " neuroprotectants" such as nimodipine, statins, and magnesium and the role of hemodynamic augmentation in vasospasm amelioration, including the use of inotropic support in addition to traditional triple-H therapy, are discussed.

Original languageEnglish (US)
Pages (from-to)353-364
Number of pages12
JournalNeurosurgery Clinics of North America
Volume21
Issue number2
DOIs
StatePublished - Apr 2010

Fingerprint

Subarachnoid Hemorrhage
Angiography
Doppler Transcranial Ultrasonography
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Nimodipine
Neuroprotective Agents
Magnesium
Perfusion
Hemodynamics
Morbidity
Mortality
Therapeutics

Keywords

  • Aneurysmal subarachnoid hemorrhage
  • Cerebral blood flow
  • Triple-H therapy
  • Vasospasm

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

Risk Factors and Medical Management of Vasospasm After Subarachnoid Hemorrhage. / Lazaridis, Christos; Naval, Neeraj.

In: Neurosurgery Clinics of North America, Vol. 21, No. 2, 04.2010, p. 353-364.

Research output: Contribution to journalArticle

Lazaridis, Christos ; Naval, Neeraj. / Risk Factors and Medical Management of Vasospasm After Subarachnoid Hemorrhage. In: Neurosurgery Clinics of North America. 2010 ; Vol. 21, No. 2. pp. 353-364.
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