Right Ventricular Function in Infants, Children and Adolescents: Reference Values of the Tricuspid Annular Plane Systolic Excursion (TAPSE) in 640 Healthy Patients and Calculation of z Score Values

Martin Koestenberger, William Ravekes, Allen D. Everett, Hans Peter Stueger, Bernd Heinzl, Andreas Gamillscheg, Gerhard Cvirn, Arnulf Boysen, Andrea Fandl, Bert Nagel

Research output: Contribution to journalArticle

Abstract

Background: Tricuspid annular plane systolic excursion (TAPSE) is an echocardiographic measurement to assess right ventricular systolic function in adults. The aim of this study was to determine growth-related changes in TAPSE to establish references values. Methods: A prospective study was conducted in a group of 640 healthy pediatric patients (age range, 1 day to 18 years; body surface area range, 0.12-2.25 m2). The effects of age and body surface area on TAPSE were determined. Results: TAPSE ranged from a mean of 0.91 cm (z score ± 3, 0.56-1.26 cm) in neonates to 2.47 cm (z score ± 3, 1.84-3.10 cm) in 18-year-olds. TAPSE values showed positive correlations with age and body surface area. There was no significant difference in TAPSE values between female or male children. Conclusion: In this study, z scores of TAPSE values were calculated and percentile charts were established to serve as reference data for ready application in patients with congenital heart disease in the future.

Original languageEnglish (US)
Pages (from-to)715-719
Number of pages5
JournalJournal of the American Society of Echocardiography
Volume22
Issue number6
DOIs
StatePublished - Jun 1 2009
Externally publishedYes

Keywords

  • Age
  • Body surface area
  • M-mode
  • Pediatric patients
  • Reference values
  • Right ventricular systolic function
  • Tricuspid annular plane systolic excursion
  • z score

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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