Right Ventricular Dysfunction in Chronic Lung Disease

Research output: Contribution to journalArticle

Abstract

Right ventricular (RV) dysfunction arises in chronic lung disease when chronic hypoxemia and disruption of pulmonary vascular beds increase ventricular afterload. RV dysfunction is defined by hypertrophy with preserved myocardial contractility and cardiac output. RV hypertrophy seems to be a common complication of chronic and advanced lung disease. RV failure is rare, except during acute exacerbations of chronic lung disease or when multiple comorbidities are present. Treatment is targeted at correcting hypoxia and improving pulmonary gas exchange and mechanics. There are no data supporting the use of pulmonary hypertension-specific therapies for patients with RV dysfunction secondary to chronic lung disease.

Original languageEnglish (US)
Pages (from-to)243-256
Number of pages14
JournalCardiology Clinics
Volume30
Issue number2
DOIs
StatePublished - May 2012

Fingerprint

Right Ventricular Dysfunction
Lung Diseases
Chronic Disease
Pulmonary Gas Exchange
Right Ventricular Hypertrophy
Patient Rights
Mechanics
Pulmonary Hypertension
Cardiac Output
Hypertrophy
Blood Vessels
Comorbidity
Lung
Hypoxia

Keywords

  • Chronic lung disease
  • Cor pulmonale
  • Pulmonary hypertension
  • Right ventricle

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Right Ventricular Dysfunction in Chronic Lung Disease. / Kolb, Todd Matthew; Hassoun, Paul M.

In: Cardiology Clinics, Vol. 30, No. 2, 05.2012, p. 243-256.

Research output: Contribution to journalArticle

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