Ribosomal translocation: Sparsomycin pushes the button

Daniel R. Southworth, Rachel Green

Research output: Contribution to journalReview articlepeer-review

Abstract

New insights into the way that the tRNA:mRNA complex is translocated on the ribosome during protein synthesis have come from the recent observation that binding of the antibiotic sparsomycin in the peptidyl transferase center can trigger these large-scale movements.

Original languageEnglish (US)
Pages (from-to)R652-R654
JournalCurrent Biology
Volume13
Issue number16
DOIs
StatePublished - Aug 19 2003

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

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